Takahashi Ippei, Obara Taku, Kikuchi Saya, Kobayashi Mika, Ishikuro Mami, Murakami Keiko, Ueno Fumihiko, Noda Aoi, Onuma Tomomi, Matsuzaki Fumiko, Kobayashi Natsuko, Hamada Hirotaka, Iwama Noriyuki, Saito Masatoshi, Sugawara Junichi, Tomita Hiroaki, Kure Shigeo, Yaegashi Nobuo, Kuriyama Shinichi
Graduate School of Medicine, Tohoku University, Sendai, Japan.
Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
J Paediatr Child Health. 2023 Mar;59(3):548-554. doi: 10.1111/jpc.16353. Epub 2023 Feb 8.
An association between maternal psychological distress and children's development has been reported, but reports from Japan are limited. This study aimed to examine the association of maternal psychological distress with children's neurodevelopment in Japan.
The study assessed data of 7646 mother-infant pairs in the Japanese population. We used Kessler Psychological Distress Scale, a screening tool for psychological distress, to assess maternal psychological distress in early pregnancy and 2 years postpartum and divided it into four categories: none in both the pre-natal and post-natal periods, only the pre-natal period, only the post-natal period and both the pre-natal and post-natal periods. Children's neurodevelopment was assessed using the Ages & Stages Questionnaires Third Edition (ASQ-3) at 4 years of age. ASQ-3 comprises five domains (communication, gross motor, fine motor, problem solving and personal-social), and the score of less than -2 standard deviation relative to the mean in reference was defined as having developmental delay. We conducted multivariate logistic regression analysis to examine the association between maternal psychological distress and children's neurodevelopment.
The prevalence of developmental delay of communication, gross motor, fine motor, problem solving and personal-social were 4.0%, 4.3%, 4.9%, 3.8% and 4.6%, respectively. Maternal psychological distress in only the postpartum period and both pre-natal and postpartum periods were associated with risks of developmental delay in all domains. Maternal psychological distress in only the pre-natal period was associated with developmental delay in communication.
Maternal psychological distress is associated with risks of children's developmental delay.
已有报道称母亲心理困扰与儿童发育之间存在关联，但来自日本的相关报道有限。本研究旨在探讨日本母亲心理困扰与儿童神经发育之间的关联。
该研究评估了日本人群中7646对母婴的数据。我们使用凯斯勒心理困扰量表（一种心理困扰筛查工具）来评估孕早期和产后2年时母亲的心理困扰，并将其分为四类：产前和产后均无困扰、仅产前有困扰、仅产后有困扰以及产前和产后均有困扰。在儿童4岁时，使用《年龄与发育进程问卷第三版》（ASQ - 3）评估其神经发育情况。ASQ - 3包括五个领域（沟通、大运动、精细运动、问题解决和个人社交），相对于参考均值低于 -2标准差的分数被定义为发育迟缓。我们进行了多因素逻辑回归分析，以检验母亲心理困扰与儿童神经发育之间的关联。
沟通、大运动、精细运动、问题解决和个人社交领域发育迟缓的患病率分别为4.0%、4.3%、4.9%、3.8%和4.6%。仅产后以及产前和产后均有心理困扰与所有领域的发育迟缓风险相关。仅产前有心理困扰与沟通方面的发育迟缓相关。
母亲心理困扰与儿童发育迟缓风险相关。
