Mustač Filip, Matovinović Martina, Mutak Tomislav, Barun Barbara, Šagud Marina, Marčinko Darko
Department of Psychiatry and Psychological Medicine, University Hospital Centre Zagreb, Zagreb, Croatia.
Psychiatr Danub. 2022 Dec;34(Suppl 10):72-78.
Obesity is one of today's most concerning health problems due to increased cardiovascular risk, which is still the leading cause of death. Obstructive sleep apnea syndrome (OSAS) is certainly one of the important risk factors that links obesity and cardiovascular risk. There is a great need to evaluate obstructive sleep apnea (OSA) in obese patients. Today, there are easily available and applicable questionnaires (Epworth Sleepiness Scale (ESS), STOP, STOP-Bang (SBQ), Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI)) that could be very useful in clinical practice for this very purpose. The aim of this paper is to investigate the sensitivity and specificity of the questionnaires for OSA screening in obese patients with and without OSA.
This cross-sectional study was carried out in the tertiary healthcare centre. The following questionnaires were used: ESS, STOP, SBQ, ISI, PSQI. 70 (58 female) adult patients with obesity (body mass index (BMI) > 30 kg/m2) were included.
SBQ showed sensitivity of 75%, specificity of 75% at cut-off of 5.5 with the Youden index of 0.5, while PSQI had sensitivity of 78%, specificity of 67% at cut-off of 17.75 with slightly smaller Youden index 0.45. STOP and ESS had a sensitivity of 77% and 75%, respectively but with an even smaller Youden index (0.23 and 0.21), and ISI had the lowest sensitivity of 59% and the lowest Youden index (0.13) of the questionnaires we examined.
Our study results suggest that SBQ and PSQI are best screening tools in detecting OSA in patients with obesity. Further study of these questionnaires and possible modifications are certainly important for future research.
肥胖是当今最令人担忧的健康问题之一，因为其会增加心血管疾病风险，而心血管疾病仍是主要的死亡原因。阻塞性睡眠呼吸暂停综合征（OSAS）无疑是将肥胖与心血管风险联系起来的重要危险因素之一。非常有必要对肥胖患者的阻塞性睡眠呼吸暂停（OSA）进行评估。如今，有一些易于获取和应用的问卷（爱泼华嗜睡量表（ESS）、STOP、STOP-Bang问卷（SBQ）、失眠严重程度指数（ISI）和匹兹堡睡眠质量指数（PSQI）），为此目的在临床实践中可能非常有用。本文旨在研究这些问卷对肥胖伴或不伴OSA患者进行OSA筛查的敏感性和特异性。
本横断面研究在三级医疗中心开展。使用了以下问卷：ESS、STOP、SBQ、ISI、PSQI。纳入了70名（58名女性）肥胖成年患者（体重指数（BMI）>30kg/m²）。
SBQ在截断值为5.5时，敏感性为75%，特异性为75%，约登指数为0.5；而PSQI在截断值为17.75时，敏感性为78%，特异性为67%，约登指数略小，为0.45。STOP和ESS的敏感性分别为77%和75%，但约登指数更小（分别为0.23和0.21），而ISI在我们所研究的问卷中敏感性最低，为59%，约登指数也最低（0.13）。
我们的研究结果表明，SBQ和PSQI是检测肥胖患者OSA的最佳筛查工具。对这些问卷的进一步研究以及可能的改进对于未来研究肯定很重要。
