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心理因素在原发性不孕女性体外受精结局中的作用

The Role of Psychological Factors in the Outcome of In Vitro Fertilization in Women with Primary Infertility.

作者信息

Ražić Pavičić Andrea, Jakšić Nenad, Jakovina Trpimir, Skočić Hanžek Milena, Miškulin Iva, Gregurek Rudolf

机构信息

Department of Psychiatry and Psychological Medicine, University Hospital Centre Zagreb, Kispatićeva 12, Zagreb, Croatia,

出版信息

Psychiatr Danub. 2022 Dec;34(Suppl 10):104-114.

PMID:36752249
Abstract

INTRODUCTION

Infertility is a multidimensional developmental crisis of the individual, couple, family and the population as a whole. This study concentrates on the psychological aspects of infertility treatment by in vitro fertilization (IVF). The aim of this study was to examine a connection between certain psychological factors - anxiety, depression, motivation for parenthood, styles of coping with stress - and the outcome of IVF.

SUBJECTS AND METHODS

The study included 100 primarily infertile women aged 23-38 years, who underwent IVF procedure for the first time, at the Department of Gynaecology and Obstetrics of University Hospital Centre Zagreb. Regarding the outcome of IVF, they were divided into two groups, those with positive outcome (N=50), and those with negative outcome of IVF (N=50). We have applied: general data questionnaire, Parenthood motivation scale, COPE Inventory, and Depression, Anxiety, Stress Scales - 21.

RESULTS

The dimension of motivation for parenthood Relationship and the styles of coping with stress Seeking emotional support, Planning and Active coping proved to be statistically significant predictors of IVF outcome. By increasing the results on the relationship, seeking emotional support and planning subscales, the likelihood of negative outcome was increased. By increasing the results on the active coping subscale, the likelihood of positive outcome was increased. Anxiety and depression symptoms did not prove to be statistically significant predictors of the IVF outcome.

CONCLUSION

The role of psychological factors is important for understanding the diagnosis and treatment of infertility. They also provide the basis for creating guidelines for specific preventive and educational programs and for special forms of psychological counselling for individuals facing infertility.

摘要

引言

不孕症是个人、夫妻、家庭乃至整个群体面临的多维度发展危机。本研究聚焦于体外受精(IVF)治疗不孕症的心理层面。本研究旨在探究某些心理因素——焦虑、抑郁、为人父母的动机、应对压力的方式——与IVF治疗结果之间的联系。

对象与方法

该研究纳入了100名年龄在23至38岁之间、首次在萨格勒布大学医院中心妇产科接受IVF治疗的原发性不孕女性。根据IVF治疗结果,她们被分为两组,一组治疗结果为阳性(N = 50),另一组IVF治疗结果为阴性(N = 50)。我们使用了:一般数据问卷、为人父母动机量表、应对方式量表以及抑郁、焦虑、压力量表 - 21。

结果

为人父母动机维度中的关系维度以及应对压力的方式维度中的寻求情感支持、计划和积极应对被证明是IVF治疗结果的统计学显著预测因素。关系维度、寻求情感支持和计划分量表得分增加,负面结果的可能性增加。积极应对分量表得分增加,正面结果的可能性增加。焦虑和抑郁症状并未被证明是IVF治疗结果的统计学显著预测因素。

结论

心理因素对于理解不孕症的诊断和治疗具有重要作用。它们还为制定特定预防和教育项目的指导方针以及为面临不孕症的个体提供特殊形式的心理咨询奠定了基础。

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Self-blame predicts anxiety and depression in infertile couples who opt for in vitro fertilisation (IVF) treatment.自责会预测选择体外受精 (IVF) 治疗的不孕夫妇的焦虑和抑郁。
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