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感染猴痘病毒和接种疫苗后发生的帕森斯-特纳综合征。

Parsonage-Turner syndrome following monkeypox infection and vaccination.

机构信息

Department of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA.

Department of Spine and Sports Medicine, Hospital for Special Surgery, New York, NY, USA.

出版信息

Skeletal Radiol. 2023 Sep;52(9):1781-1784. doi: 10.1007/s00256-023-04298-4. Epub 2023 Feb 8.

Abstract

Beginning in May 2022, monkeypox infection and vaccination rates dramatically increased due to a worldwide outbreak. This case highlights magnetic resonance (MR) neurography findings in an individual who developed Parsonage-Turner syndrome (PTS) 5 days after monkeypox symptom onset and 12 days after receiving the JYNNEOS vaccination. MR neurography of the patient's left suprascapular nerve demonstrated intrinsic hourglass-like constrictions, a characteristic finding of peripheral nerves involved in PTS. Other viral infections and vaccinations are well-documented triggers of PTS, an underrecognized peripheral neuropathy that is thought to be immune-mediated and results in severe upper extremity pain and weakness. The close temporal relationship between monkeypox infection and vaccination, and PTS onset, in this case, suggests a causal relationship and marks the first known report of peripheral neuropathy associated with monkeypox.

摘要

从 2022 年 5 月开始,由于全球范围内的爆发,猴痘感染和疫苗接种率大幅上升。本病例突出了磁共振(MR)神经成像在个体中的发现,该个体在猴痘症状出现后 5 天和接受 JYNNEOS 疫苗接种后 12 天发展为 Parsonage-Turner 综合征(PTS)。患者左侧肩胛上神经的 MR 神经成像显示固有沙漏样狭窄,这是 PTS 累及周围神经的特征性表现。其他病毒感染和疫苗接种是 PTS 的明确触发因素,PTS 是一种认识不足的周围神经病,被认为是免疫介导的,导致严重的上肢疼痛和无力。在本例中,猴痘感染和疫苗接种与 PTS 发病之间的密切时间关系表明存在因果关系,并标志着首例与猴痘相关的周围神经病的已知报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aea/9907186/1dc152ac416c/256_2023_4298_Fig1_HTML.jpg

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