Sheen R, MacLeod A M, O'Brien B M
Microsurgery Research Centre, St Vincent's Hospital, Fitzroy, Victoria, Australia.
Aust N Z J Surg. 1987 Aug;57(8):559-63. doi: 10.1111/j.1445-2197.1987.tb01421.x.
An evaluation of the effect of ischaemia upon the intraluminal pH of microvascular free jejunal autografts was undertaken with a view to developing a monitoring system to be used clinically. Employing a canine model, the intraluminal pH of isolated jejunal segments was measured during normal perfusion and under conditions of arterial and venous occlusion. Ischaemia induced a rapid, easily measured fall in intraluminal pH reversible after 1 h of normothermic ischaemia. The most rapid pH change occurred within the first 10 min. It is felt that continuous intraluminal pH measurement may form a reliable method of monitoring the postoperative vascular perfusion of clinical free jejunal transfers.
为了开发一种可用于临床的监测系统，对缺血对游离空肠微血管自体移植管腔内pH值的影响进行了评估。采用犬模型，在正常灌注以及动脉和静脉阻塞条件下，测量分离空肠段的管腔内pH值。缺血导致管腔内pH值迅速下降，且易于测量，在常温缺血1小时后可恢复。pH值变化最快发生在最初10分钟内。人们认为，持续测量管腔内pH值可能形成一种可靠的方法，用于监测临床游离空肠移植术后的血管灌注情况。
