Gut Microbes & Health, Quadram Institute Bioscience, Norwich Research Park, Norwich, NR4 7UQ, UK.
Intestinal Microbiome, School of Life Sciences, ZIEL - Institute for Food & Health, Technical University of Munich, Freising, 80333, Germany.
Anaerobe. 2023 Apr;80:102713. doi: 10.1016/j.anaerobe.2023.102713. Epub 2023 Feb 6.
Prophylactic administration of oral probiotics is associated with significant reductions in the morbidity and mortality of necrotising enterocolitis in preterm infants. We document the first case of Bifidobacterium longum subsp. infantis sub-clinical bacteraemia, in an extremely low birth weight preterm infant, since introduction of routine probiotic treatment at the Norfolk and Norwich University Hospital 10 years ago. Whole genome comparisons confirmed the isolated strain likely originated from the probiotic product.
预防性口服益生菌可显著降低早产儿坏死性小肠结肠炎的发病率和死亡率。我们报道了自 10 年前诺福克和诺维奇大学医院开始常规使用益生菌治疗以来，首例双歧杆菌长亚种。婴儿亚种亚临床菌血症极低出生体重早产儿的病例。全基因组比较证实，分离株可能源自益生菌产品。
