Ellwood D A, Sutherland P, Kent C, O'Connor M
Division of Obstetrics and Gynaecology, King George V Memorial Hospital for Mothers and Babies, Sydney.
Aust N Z J Obstet Gynaecol. 1987 May;27(2):92-8. doi: 10.1111/j.1479-828x.1987.tb00952.x.
A retrospective analysis has been made of the outcome of pregnancy in 174 women abusing narcotics, managed by a specialist team from a drug-dependency antenatal clinic. These women were cared for through 182 pregnancies of greater than 20 weeks' gestation, resulting in 183 live and 5 stillbirths. The majority of patients were enrolled in a methadone programme and stabilized on the drug before the third trimester. The group was characterized by a high prevalence of previous obstetric and medical problems. The most common antenatal complications were preterm labour (24%) and anaemia (12%). Preterm delivery and small-for-gestational-age each occurred in a quarter of pregnancies. The mean birth-weight for the group was 2,746 g +/- 721 g; mean +/- S.D. Eight perinatal deaths occurred (5 stillbirths, 3 neonatal deaths), giving a perinatal mortality rate of 43/1,000. The data on narcotic abusers have been compared with similar data obtained from randomly selected public antenatal clinic patients who delivered during the same period.
对174名滥用麻醉品的妇女的妊娠结局进行了回顾性分析，这些妇女由药物依赖产前诊所的专业团队管理。这些妇女经历了182次妊娠，妊娠周数均超过20周，共分娩出183名活产婴儿和5名死产婴儿。大多数患者参加了美沙酮项目，并在孕晚期之前病情稳定。该组的特点是既往产科和内科问题的患病率较高。最常见的产前并发症是早产（24%）和贫血（12%）。四分之一的妊娠出现早产和小于胎龄儿。该组的平均出生体重为2746克±721克；均值±标准差。发生了8例围产期死亡（5例死产，3例新生儿死亡），围产儿死亡率为43‰。已将麻醉品滥用者的数据与同期从随机选择的公立产前诊所分娩患者中获得的类似数据进行了比较。
