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Inhibiting Both Neprilysin and Phosphodiesterase Type 9: Turning on the Faucet While Plugging the Sink.

作者信息

Kass David A

机构信息

Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

出版信息

JACC Heart Fail. 2023 Feb;11(2):240-242. doi: 10.1016/j.jchf.2022.12.003.

DOI:10.1016/j.jchf.2022.12.003
PMID:36754530
Abstract
摘要

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Long-term treatment with a phosphodiesterase type 5 inhibitor improves pulmonary hypertension secondary to heart failure through enhancing the natriuretic peptides-cGMP pathway.5型磷酸二酯酶抑制剂的长期治疗通过增强利钠肽-cGMP途径改善继发于心力衰竭的肺动脉高压。
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