Furr P A
Grumman Space Systems Division, Bethpage, NY 11714.
Aviat Space Environ Med. 1987 Sep;58(9 Pt 2):A113-20.
Breathing oxygen at high partial pressure is toxic to all systems of the body. However, the effect a of a high PO2 on the pulmonary and erythropoietic systems pose the greatest threat to the EVA astronaut utilizing a single gas space suit system. Oxygen toxicity has been studied extensively, and a review of the literature suggests that continuous exposure to a PO2 of 8 psi can be tolerated indefinitely and should not present the astronaut with a problem for the Extravehicular Activity (EVA) scenarios projected for Space Station. However, the cause of the decrease in circulating red blood cell mass, which has been shown to accompany exposure to microgravity as well as hyperoxemia, is not as well defined when both conditions are simultaneously present.
在高分压下呼吸氧气对身体的所有系统都有毒性。然而,高分压的PO₂对肺部和红细胞生成系统的影响,对使用单气体航天服系统的舱外活动(EVA)宇航员构成了最大威胁。氧气毒性已得到广泛研究,文献综述表明,持续暴露于8磅力/平方英寸的PO₂可无限期耐受,并且对于空间站预计的舱外活动(EVA)场景,不应给宇航员带来问题。然而,当同时存在微重力暴露和高氧血症时,循环红细胞量减少的原因尚未明确,已有研究表明这种减少与微重力暴露以及高氧血症有关。