Morisaki I, Shimono T, Kohno N, Stewart-Tull D E, Kotani S, Kitamura H
Department of Microbiology and Oral Microbiology, Osaka University Faculty of Dentistry, Japan.
Biken J. 1987 Mar;30(1):9-16.
Antigen solution could be injected into the cornea of sensitized mice using a fine needle and a stereoscopic dissecting microscope. The resulting corneal reaction was shown to be a reliable method in the detection and estimation of delayed-type hypersensitivity in mice that had been immunized with a water-in-oil emulsion containing an ovalbumin and a cell wall adjuvant. Unlike the delayed skin reaction in the ear lobe, this corneal reaction was not affected by a coexisting Arthus reaction.
可使用细针和体视解剖显微镜将抗原溶液注射到致敏小鼠的角膜中。结果表明，这种角膜反应是检测和评估用含有卵清蛋白和细胞壁佐剂的油包水乳液免疫的小鼠迟发型超敏反应的可靠方法。与耳垂的迟发性皮肤反应不同，这种角膜反应不受同时存在的阿瑟斯反应的影响。
