Ledibane Tladi D, Ledibane Neo R, Matlala Moliehi
Department of Public Health Medicine, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa.
School of Health Systems and Public Health, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
S Afr J Infect Dis. 2023 Jan 31;38(1):492. doi: 10.4102/sajid.v38i1.492. eCollection 2023.
Human papillomavirus (HPV) vaccine is an effective preventive measure against HPV infection and HPV-associated cervical cancer. South Africa introduced its HPV vaccination programme in 2014.
The authors assessed the uptake of HPV vaccine in the school-based HPV vaccination programme in Tshwane Health District for the year 2019 and compared the vaccine uptake (VU) between fee-paying and no-fee public schools.
The study method was cross-sectional, using routine electronic health records of the HPV vaccination programme. The study population included all Grade 4 school-girls between the ages of 9 and 14 years who attended public schools in 2019 in the Tshwane Health District.
The pooled VU for the Tshwane Health District was 72.0%, considerably lower than the target of 80.0%. The number of girls who received dose one and dose two in 2019 was 16 122 (73.0%) and 15 734 (71.0%), respectively, excluding the catch-up figures. In addition, 82.2% of fee-paying schools achieved VU of above 80% versus 65.5% of no-fee schools ( = 0.022).
The lower than target levels of VU for HPV among girls in Tshwane Health District, particularly in those attending no-fee schools, is concerning. Interventions should be adopted to optimise programme performance so as to achieve the target VU of 80%.
This study showed the need to strengthen sensitisation and social mobilisation efforts, particularly among no-fee schools to improve the VU.
人乳头瘤病毒（HPV）疫苗是预防HPV感染和HPV相关宫颈癌的有效措施。南非于2014年推出了HPV疫苗接种计划。
作者评估了茨瓦内健康区2019年在校HPV疫苗接种计划中HPV疫苗的接种情况，并比较了收费公立学校和免费公立学校之间的疫苗接种率（VU）。
研究方法为横断面研究，使用HPV疫苗接种计划的常规电子健康记录。研究人群包括2019年在茨瓦内健康区就读公立学校的所有9至14岁四年级女生。
茨瓦内健康区的综合疫苗接种率为72.0%，远低于80.0%的目标。2019年接受第一剂和第二剂疫苗的女孩人数分别为16122人（73.0%）和15734人（71.0%），不包括补种数据。此外，82.2%的收费学校疫苗接种率达到80%以上，而免费学校为65.5%（P = 0.022）。
茨瓦内健康区女孩的HPV疫苗接种率低于目标水平，尤其是在免费学校就读的女孩中，这令人担忧。应采取干预措施以优化计划执行情况，从而实现80%的目标疫苗接种率。
本研究表明有必要加强宣传和社会动员工作，尤其是在免费学校中，以提高疫苗接种率。
