Department of Clinical Neurosciences, The University of Edinburgh, 50 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom; Department of Clinical and Health Psychology, The University of Edinburgh, Medical Quad, Teviot Place, Edinburgh EH8 9AG, United Kingdom.
Department of Clinical and Health Psychology, The University of Edinburgh, Medical Quad, Teviot Place, Edinburgh EH8 9AG, United Kingdom.
Seizure. 2023 Mar;106:39-49. doi: 10.1016/j.seizure.2023.01.016. Epub 2023 Jan 30.
Illness representations refer to a person's beliefs about their health condition and are thought to influence clinical outcomes. By understanding factors related to illness representations, potentially modifiable targets for psychological intervention can be identified. The aim of this systematic review was to synthesise the literature on factors associated with illness representations in people with epilepsy and functional seizures. Three electronic databases (Psychinfo, EMBASE, and Proquest (Theses and dissertations)) were searched for studies that reported on associations between Illness Perception Questionnaire scores (or variations thereof) and biopsychosocial factors in people with epilepsy or people with functional seizures. Seventeen studies met inclusion criteria and were assessed with a bespoke quality appraisal tool. Overall, there was moderately strong evidence for an association between more threatening illness representations and poorer clinical outcomes relating to seizure characteristics, distress, coping, and quality of life; the evidence for these relationships was stronger for people with epilepsy than functional seizures. There was no clear difference between the illness representations of the two groups. The results of this review highlight the clinical importance of illness representations in people with seizure disorders, as well as opportunities for further research.
疾病认知是指个体对自身健康状况的信念，被认为会影响临床结局。通过了解与疾病认知相关的因素，可以确定潜在的可干预的心理干预目标。本系统综述旨在综合有关癫痫和功能性癫痫患者疾病认知相关因素的文献。通过检索三个电子数据库（Psychinfo、EMBASE 和 ProQuest（论文和学位论文）），寻找报告癫痫或功能性癫痫患者的疾病感知问卷评分（或其变体）与生物心理社会因素之间关联的研究。符合纳入标准的 17 项研究采用专门的质量评估工具进行了评估。总体而言，更具威胁性的疾病认知与与癫痫特征、痛苦、应对方式和生活质量相关的较差临床结局之间存在中度强关联证据；对于癫痫患者而言，这些关联的证据更强。两组患者的疾病认知之间没有明显差异。本综述的结果强调了疾病认知在癫痫患者中的临床重要性，以及进一步研究的机会。
