Smith Catherine L, Gao Caroline X, Xu Rongbin, Ikin Jillian F, Dimitriadis Christina, Carroll Matthew Tc, Sim Malcolm R, Stub Dion, Lane Tyler J, Abramson Michael J, Guo Yuming
School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, Victoria, 3004, Australia.
School of Public Health and Preventive Medicine, Monash University, 553 St Kilda Road, Melbourne, Victoria, 3004, Australia; Centre for Youth Mental Health, The University of Melbourne, Parkville, VIC, 3052, Australia; Orygen, Parkville, VIC, 3052, Australia.
Environ Res. 2023 Apr 15;223:115440. doi: 10.1016/j.envres.2023.115440. Epub 2023 Feb 8.
In 2014, wildfires ignited a coal mine in Australia, burning for 6 weeks, releasing large amounts of fine particulate matter ≤2.5 μm in diameter (PM). We investigated the association between individual PM exposure and emergency department presentations (EDPs) within 5 years post-fire.
Survey and exposure data for 2725 residents from an exposed and unexposed town were linked with ED administrative data from 2009 to 2019. The association between individual PM and EDPs was assessed using recurrent survival analysis.
A 10 μg/m increase in PM was associated with a 10% increase in respiratory EDPs (HR = 1.10; 95%CI:1.00-1.22) over 5 years post-fire. Increased risks of EDPs for ischaemic heart disease (HR = 1.39; 95%CI:1.12-1.73), atherothrombotic disease (HR = 1.27; 95%CI:1.08-1.50), and cardiovascular disease (HR = 1.10, 95%CI:0.99-1.22) were evident within 2.5 years.
PM exposure from a 6-week mine fire increased the 5-year risk of respiratory conditions. An increased risk of CVD within 2.5 years post-fire subsided after this time.
2014年，澳大利亚一场野火点燃了一座煤矿，燃烧持续了6周，释放出大量直径≤2.5微米的细颗粒物（PM）。我们调查了火灾发生后5年内个体接触PM与急诊就诊（EDP）之间的关联。
将来自一个暴露和未暴露城镇的2725名居民的调查和暴露数据与2009年至2019年的急诊管理数据相联系。使用复发生存分析评估个体PM与EDP之间的关联。
火灾发生后5年内，PM每增加10微克/立方米，呼吸道EDP增加10%（风险比[HR]=1.10；95%置信区间[CI]：1.00-1.22）。在2.5年内，缺血性心脏病（HR=1.39；95%CI：1.12-1.73）、动脉粥样硬化血栓形成疾病（HR=1.27；95%CI：1.08-1.50）和心血管疾病（HR=1.10，95%CI：0.99-1.22）的EDP风险增加明显。
为期6周的煤矿火灾造成的PM暴露增加了呼吸道疾病的5年风险。火灾发生后2.5年内心血管疾病风险增加，此后风险消退。
