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小儿肠伤寒误诊为克罗恩病合并腹腔结核

Enteric fever masquerading as Crohn's disease in a child with abdominal tuberculosis.

机构信息

Pediatrics, Indraprastha Apollo Hospital, New Delhi, India

Pediatric Gastroenterology and Hepatology, Indraprastha Apollo Hospital, New Delhi, India.

出版信息

BMJ Case Rep. 2023 Feb 9;16(2):e249531. doi: 10.1136/bcr-2022-249531.

DOI:10.1136/bcr-2022-249531
PMID:36759044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9923286/
Abstract

In tropical countries, like India, various types of infectious diseases like tuberculosis, enteric fever, malaria and dengue are prevalent. Disease trend over time has been gradually shifting from infective to inflammatory frame because of increasing awareness regarding hygiene and increasing immunisation coverage. This case report describes an adolescent boy having a long history of abdominal pain, bleeding per rectum and documented weight loss, presented with an acute episode of fever. But the coexisting infections and/or inflammatory conditions presented challenges to the treating physician in diagnosis and management despite of good clinical experience. In this case, a chronic gastrointestinal infection caused by with a superadded Salmonella typhi infection was masquerading as inflammatory bowel disease (Crohn's disease). Utmost caution should be exercised to reach the correct diagnosis and take the necessary steps to manage this type of situation in tropical countries like India.

摘要

在印度等热带国家,结核病、肠热病、疟疾和登革热等各种传染病较为流行。由于人们对卫生的认识不断提高,免疫接种覆盖率不断增加,疾病的流行趋势逐渐从感染性疾病向炎症性疾病转变。本病例报告描述了一名青少年男性,长期腹痛、直肠出血和体重减轻,因急性发热就诊。但共存的感染和/或炎症状况给治疗医生的诊断和治疗带来了挑战,尽管他们有丰富的临床经验。在这种情况下,由 引起的慢性胃肠道感染,合并伤寒沙门氏菌感染,表现为炎症性肠病(克罗恩病)。在印度等热带国家,应格外小心,以做出正确诊断,并采取必要措施来处理这种情况。

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Enteric fever masquerading as Crohn's disease in a child with abdominal tuberculosis.小儿肠伤寒误诊为克罗恩病合并腹腔结核
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Differentiation of Crohn's disease from intestinal tuberculosis in India in 2010.2010 年印度克罗恩病与肠结核的鉴别诊断。
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[Diagnosis and treatment of Crohn's disease and intestinal tuberculosis].[克罗恩病与肠结核的诊断和治疗]
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引用本文的文献

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Abdominal tuberculosis in children: a systematic review on current advances.儿童腹部结核病:当前进展的系统评价
Pediatr Surg Int. 2025 Jun 18;41(1):175. doi: 10.1007/s00383-025-06080-0.

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Abdominal tuberculosis in children: A real-world experience of 218 cases from an endemic region.儿童腹部结核:来自一个地方病流行地区218例病例的真实世界经验
JGH Open. 2019 Aug 20;4(2):215-220. doi: 10.1002/jgh3.12245. eCollection 2020 Apr.
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Dramatic Increase in Incidence of Ulcerative Colitis and Crohn's Disease (1988-2011): A Population-Based Study of French Adolescents.溃疡性结肠炎和克罗恩病发病率的急剧上升(1988-2011):基于人群的法国青少年研究。
Am J Gastroenterol. 2018 Feb;113(2):265-272. doi: 10.1038/ajg.2017.228. Epub 2017 Aug 15.
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European consensus on the histopathology of inflammatory bowel disease.欧洲炎症性肠病组织病理学共识。
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Crohn disease of the small bowel: comparison of CT enterography, MR enterography, and small-bowel follow-through as diagnostic techniques.小肠克罗恩病:CT小肠造影、磁共振小肠造影和小肠钡剂造影作为诊断技术的比较
Radiology. 2009 Jun;251(3):751-61. doi: 10.1148/radiol.2513081184. Epub 2009 Mar 10.
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Patterns of morbidity and mortality in typhoid fever dependent on age and gender: review of 552 hospitalized patients with diarrhea.伤寒热发病率和死亡率模式与年龄和性别的关系:552例腹泻住院患者回顾
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