Fenton S S, Johnston N, Delmore T, Detsky A S, Whitewell J, O'Sullivan R, Cattran D C, Richardson R M, Jeejeebhoy K N
Department of Medicine, Toronto General Hospital, Ontario, Canada.
ASAIO Trans. 1987 Jul-Sep;33(3):650-3.
This study revealed the following. Malnutrition was frequent (41.6%) in patients on CAPD for less than three months and was present in 18.1% of patients on CAPD for longer than 3 months. Fifty percent of these malnourished patients returned to normal on conventional nutritional management within 2 to 6 months, but 10% remained malnourished throughout the study period. There was increased mortality among malnourished patients, but we were unable to demonstrate that the state of nutrition was an independent risk factor, because of the increased prevalence of other co-morbid risk factors known to influence survival and because of the limitation of a small sample size. The influence, if any, of nutritional state as an independent risk factor on the survival of CAPD patients should be answered, because malnutrition is potentially reversible with aggressive nutritional interventions, such as enteral, parenteral, or intraperitoneal supplementation.
本研究揭示了以下情况。在接受持续非卧床腹膜透析（CAPD）不足三个月的患者中，营养不良情况很常见（41.6%），而在接受CAPD超过三个月的患者中，这一比例为18.1%。这些营养不良的患者中有50%在2至6个月内通过传统营养管理恢复正常，但10%在整个研究期间仍处于营养不良状态。营养不良患者的死亡率有所增加，但由于已知影响生存的其他合并症风险因素的患病率增加以及样本量较小的局限性，我们无法证明营养状况是一个独立的风险因素。由于营养不良通过积极的营养干预措施（如肠内、肠外或腹膜内补充）可能是可逆的，因此应明确营养状况作为独立风险因素对CAPD患者生存的影响（如果有影响的话）。
