Iannaccone Sandro, Brugliera Luigia, Spina Alfio, Nocera Gianluca, Tettamanti Andrea, Giordani Alessandra, Angelone Sara, Castellazzi Paola, Cimino Paolo, Padul Jeffrey D, Houdayer Elise, Alemanno Federica
Department of Rehabilitation and Functional Recovery.
Department of Neurosurgery and Gamma Knife Radiosurgery, IRCCS San Raffaele Scientific Institute, Milan, Italy.
J Rehabil Med Clin Commun. 2023 Jan 31;6:2222. doi: 10.2340/jrmcc.v6.2222. eCollection 2023.
We aimed to investigate the clinical symptoms and specific care requirements of SARS-CoV-2 patients who were admitted to a COVID-19 Rehabilitation Unit while still infectious for SARS-CoV-2 and in the subacute phase of the disease.
Patients admitted to our COVID-19 Rehabilitation Unit from March 2020 to December 2020 were evaluated for sarcopenia, and they also completed the following assessments: functional independence measure, short physical performance battery and Hamilton Rating Scale for Depression. Age and body mass index and symptoms of dysosmia or dysgeusia were also recorded.
A total of 126 patients were enrolled (50 women, median age 72 years, 18.7 years), of whom 82% of patients presented with low grip strength. Sarcopenia was diagnosed in 52 patients. Sarcopenic patients were older than non-sarcopenic ones (median age 73.4 years, IQR 13.2 vs 63.9 years, IQR 14.5, respectively, = 0.014). Sarcopenia was associated with the presence of depression ( = 0.008), was more common in women ( = 0.023) and was associated with greater functional deficits (functional independence measure and short physical performance battery analyses, < 0.05). Sarcopenic patients also had a lower body mass index than other patients ( < 0.01).
More than 40% of our patients suffered from sarcopenia, which was associated with ageing, depression, low body mass index, reduction in functional autonomy and being a woman. Such data provide evidence for the need to assist hospitalized COVID-19 patients by means of a multidisciplinary specialist team.
我们旨在调查新型冠状病毒2型（SARS-CoV-2）感染患者在仍具传染性且处于疾病亚急性期时入住新型冠状病毒肺炎（COVID-19）康复病房的临床症状及特殊护理需求。
对2020年3月至2020年12月入住我们COVID-19康复病房的患者进行肌肉减少症评估，他们还完成了以下评估：功能独立性测量、简短体能测试和汉密尔顿抑郁量表。同时记录患者的年龄、体重指数以及嗅觉或味觉障碍症状。
共纳入126例患者（50名女性，中位年龄72岁，四分位间距18.7岁），其中82%的患者握力较低。52例患者被诊断为肌肉减少症。肌肉减少症患者比非肌肉减少症患者年龄更大（中位年龄分别为73.4岁，四分位间距13.2岁和63.9岁，四分位间距14.5岁，P = 0.014）。肌肉减少症与抑郁症的存在相关（P = 0.008），在女性中更常见（P = 0.023），并且与更大的功能缺陷相关（功能独立性测量和简短体能测试分析，P < 0.05）。肌肉减少症患者的体重指数也低于其他患者（P < 0.01）。
我们超过40%的患者患有肌肉减少症，这与衰老、抑郁、低体重指数、功能自主性降低以及女性身份有关。这些数据为需要通过多学科专家团队协助住院COVID-19患者提供了证据。
