Iijima S, Naito Y, Naito S, Uyeno K
Department of Dermatology, University of Tsukuba, Ibaraki, Japan.
Br J Dermatol. 1987 Oct;117(4):503-10. doi: 10.1111/j.1365-2133.1987.tb04931.x.
We have recently seen two cases of hyperpigmentation in children, which was reticulate and distributed in a zosteriform fashion. As another two cases of hyperpigmentation of this kind in children have been reported previously, described as reticulate hyperpigmentation distributed in a zosteriform fashion, this gives a total of four cases of hyperpigmentation of this kind reported recently from Japan. These four cases differed from progressive cribriform and zosteriform hyperpigmentation, the condition which these cases resembled most closely, with respect to the age of onset of the hyperpigmentation, which in the four Japanese cases was not confined to a dermatome. Like a variant of incontinentia pigmenti (IP), all four cases showed eosinophilia. But they differed from IP in that there was no inflammatory stage, no pigmentary incontinence detectable on histology, and no evidence that the condition was hereditary. These four cases do not conform completely to any described entities and we suggest that they represent a new clinical entity.
我们最近见到两例儿童色素沉着过度病例,其表现为网状,呈带状分布。此前已有另外两例此类儿童色素沉着过度病例的报道,描述为呈带状分布的网状色素沉着过度,这样一来,近期来自日本的此类色素沉着过度病例共有四例。这四例病例与进行性筛状和带状色素沉着过度不同,后者是这些病例最相似的病症,在色素沉着过度的发病年龄方面存在差异,这四例日本病例并不局限于一个皮节。如同色素失禁症(IP)的一种变体,所有四例病例均表现出嗜酸性粒细胞增多。但它们与IP的不同之处在于,没有炎症阶段,组织学检查未发现色素失禁,且没有证据表明该病症具有遗传性。这四例病例并不完全符合任何已描述的实体,我们认为它们代表一种新的临床实体。