Liu Yujiao, Yu Han, Dong Youhong, Zhang Dongdong
State Key Laboratory of Separation Membranes and Membrane Processes, School of Chemistry, Tiangong University, Tianjin, China.
Department of Pathology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.
Front Oncol. 2023 Jan 25;13:1062138. doi: 10.3389/fonc.2023.1062138. eCollection 2023.
Globally, lung cancer is the leading cause of cancer-related mortality. Multiple primary lung cancers (MPLC) account for a very small portion of all primary lung cancer cases. Importantly, a quick and precise differentiation between MPLC and intrapulmonary metastases is directly related to patient prognoses as treatment strategies vary according to pathological type. Synchronous MPLC are most commonly seen in the same lung. Here, we report a rare case of a patient with synchronous MPLC of both lungs. A 67-year-old man, with a 1-month cough and expectoration history, was admitted in our hospital. Computed tomography (CT) chest scan revealed a lower lobe nodule in the left lung and an upper lobe nodule in the right lung. He underwent successive fiberoptic bronchoscopy and CT-guided percutaneous pulmonary aspiration biopsy of both lungs. The pathological diagnosis was squamous cell carcinoma of the left lung and adenocarcinoma of the right lung.
在全球范围内，肺癌是癌症相关死亡的主要原因。多原发性肺癌（MPLC）在所有原发性肺癌病例中所占比例非常小。重要的是，MPLC与肺内转移之间的快速准确区分直接关系到患者的预后，因为治疗策略会根据病理类型而有所不同。同步性MPLC最常见于同一侧肺脏。在此，我们报告一例罕见的双侧同步性MPLC患者。一名67岁男性，有1个月咳嗽咳痰病史，入住我院。胸部计算机断层扫描（CT）显示左肺下叶结节及右肺上叶结节。他接受了双侧连续纤维支气管镜检查及CT引导下经皮肺穿刺活检。病理诊断为左肺鳞状细胞癌及右肺腺癌。
