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重症监护病房术后腹膜炎的治疗:46例回顾性研究

[Treatment of postoperative peritonitis in the Intensive Care Unit: a retrospective study of 46 cases].

作者信息

Benlamkaddem Said, Houari Nawfal, Bouazzaoui Abderrahim El, Boukatta Brahim, Sbai Hicham, Kanjaa Nabil

机构信息

Service de Réanimation Polyvalente A4, Centre Hospitalier Universitaire Hassan II, Fès, Maroc.

出版信息

Pan Afr Med J. 2022 Nov 4;43:125. doi: 10.11604/pamj.2022.43.125.14331. eCollection 2022.

Abstract

We conducted a study of 46 patients admitted to the Intensive Care Unit with postoperative peritonitis. The incidence of postoperative peritonitis in this setting was 2.7%. The average age of patients was 53.3 years, with a sex ratio of 1.2. Submesocolic surgery was the most common cause of postoperative peritonitis (65.2%), mainly occurring in the colorectal region (48%). Clinical signs were dominated by fever (78%), abdominal pain (57%) and extra-abdominal signs. The mean time between symptom onset and diagnosis was 7.3 days. Reoperation was performed on the basis of clinical and biological criteria in 56.5% of cases. Therapeutic management was based on perioperative reanimation, treatment of organ dysfunctions, probabilistic antibiotic therapy and middle laparotomy. The bacteriological profile was dominated by BGN (79%). The loosening of the anastomotic sutures was the direct cause of PPO in 57% of patients. Mortality rate was 60%. The main prognostic factors were: renal failure, the number of patients with organ failure, PT<50%, the need for ventilation and the use of catecholamines.

摘要

我们对46例入住重症监护病房的术后腹膜炎患者进行了研究。这种情况下术后腹膜炎的发生率为2.7%。患者的平均年龄为53.3岁,男女比例为1.2。结肠系膜下手术是术后腹膜炎最常见的原因(65.2%),主要发生在结直肠区域(48%)。临床症状以发热(78%)、腹痛(57%)和腹部外体征为主。症状出现到诊断的平均时间为7.3天。56.5%的病例根据临床和生物学标准进行了再次手术。治疗管理基于围手术期复苏、器官功能障碍的治疗、经验性抗生素治疗和中腹部剖腹术。细菌学特征以革兰氏阴性菌(79%)为主。57%的患者吻合口缝线松动是术后腹膜炎的直接原因。死亡率为60%。主要的预后因素包括:肾衰竭、器官衰竭患者数量、凝血酶原时间<50%、需要通气以及使用儿茶酚胺。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbc9/9883798/2c7029f4da40/PAMJ-43-125-g001.jpg

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