Fan Xiulei, Qian Shenwen, Bao Yiquan, Sha Haidi, Liu Yiming, Cao Binwen
School of Environmental Engineering, Xuzhou University of Technology, Xuzhou, 221018, China; College of Environment, Hohai University, Nanjing, 210098, China; Suzhou Litree Ultra-Filtration Membrane Technology Co., Ltd., Suzhou, 215000, China.
School of Environmental Engineering, Xuzhou University of Technology, Xuzhou, 221018, China.
Environ Pollut. 2023 Apr 15;323:121252. doi: 10.1016/j.envpol.2023.121252. Epub 2023 Feb 8.
Microplastics (MPs) are widely distributed throughout the environment. Upon ingesting MPs, the pollutants that they carry are then desorbed into organisms. This results in the accumulation of various chemicals within the organism. This study systematically examined the mechanism of antibiotic desorption using tire wear particles (TWP) as a carrier of antibiotics in simulated human gastrointestinal fluid and fish intestinal fluid. The findings of this study revealed the formation of cracks, pores, and depressions on the surface of photoaged TWP in an aquatic environment, as well as additional adsorption sites that are more favorable for the attachment of pollutants. Furthermore, the simulated human gastric fluid had a higher desorption rate than that of the fish intestinal fluid. The competition for TWP adsorption sites in the gastrointestinal fluid and the potential dissolution of antibiotics were the primary drivers of the increase in the desorption rate. The desorption rate in the simulated human gastrointestinal fluid was greater than that in the simulated fish intestinal fluid due to the composition of the gastrointestinal fluid. However, the carrying of pollutants by MPs poses a potential threat to human health. This study improves our understanding of TWP toxicity and has significant implications for the development of risk assessments.
微塑料（MPs）广泛分布于整个环境中。生物体摄入微塑料后，其所携带的污染物会解吸到生物体内。这导致各种化学物质在生物体内积累。本研究以轮胎磨损颗粒（TWP）作为抗生素在模拟人体胃肠液和鱼肠液中的载体，系统地研究了抗生素的解吸机制。该研究结果表明，在水生环境中，光老化的TWP表面会形成裂缝、孔隙和凹陷，以及更有利于污染物附着的额外吸附位点。此外，模拟人体胃液的解吸率高于鱼肠液。胃肠液中TWP吸附位点的竞争以及抗生素的潜在溶解是解吸率增加的主要驱动因素。由于胃肠液的成分，模拟人体胃肠液中的解吸率高于模拟鱼肠液。然而，微塑料携带污染物对人类健康构成潜在威胁。本研究增进了我们对TWP毒性的理解，对风险评估的发展具有重要意义。
