Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Immunopathology and Cancer Biomarkers Unit - Aviano, Italy.
Department of Diagnostics and Public Health, Verona University - Verona, Italy.
Anaerobe. 2023 Apr;80:102715. doi: 10.1016/j.anaerobe.2023.102715. Epub 2023 Feb 9.
A total of 866 anaerobic strains isolated from clinical samples were tested by E-TEST for antimicrobial susceptibility. The most frequent antimicrobial resistance among the isolated genera, both Gram-positive and Gram-negative, was observed for clindamycin, and therefore, it cannot be considered as an empirical treatment. The antimicrobial resistance to benzylpenicillin was predominant among the Gram-negative bacteria, in particular the Bacteroides spp. The resistance percentages to meropenem and metronidazole are still low. However, metronidazole showed a considerable resistance in Finegoldia magna isolates, alone or in combination with other antibiotics. These data provide novel and useful epidemiological information on infections promoted by anaerobic bacteria.
共对 866 株来自临床样本的厌氧菌株进行了 E-TEST 药敏试验。在所分离的革兰阳性和革兰阴性菌属中，克林霉素的耐药率最高，因此不能将其作为经验性治疗。革兰阴性菌对苯唑西林的耐药率最高，特别是拟杆菌属。美罗培南和甲硝唑的耐药率仍然较低。然而，甲硝唑对单独或与其他抗生素联合使用的大芬戈尔氏菌的耐药性相当高。这些数据为厌氧菌引起的感染提供了新的有用的流行病学信息。
