Gorbunov N V, Konovalov G V, Taros L Iu, Abdurasulova I N, Semenov S P
Biull Eksp Biol Med. 1987 Nov;104(11):539-43.
The influence of influenza virus infection on the brain cells was studied in mice. Virology, electron microscopy and biochemistry methods were used for this purpose. It has been shown that intracerebral injection of pathogenic strain of influenza virus A/PR/8/34 is accompanied both by the reproduction of virus in the central nervous system tissue and the morphology changes in ependial cells of the vascular plexus of the brain lateral ventricle. It has been found that the level of the lipid peroxidation products in lipid extracts of infected mouse brain is greater than their level in extracts from control mouse brain. It has been concluded that the influenza virus has a damaging effect on the central nervous system cells.
在小鼠中研究了流感病毒感染对脑细胞的影响。为此采用了病毒学、电子显微镜和生物化学方法。结果表明，脑内注射甲型流感病毒A/PR/8/34的致病株，会伴随病毒在中枢神经系统组织中的繁殖以及脑侧脑室血管丛室管膜细胞的形态变化。已发现感染小鼠脑脂质提取物中脂质过氧化产物的水平高于对照小鼠脑提取物中的水平。得出的结论是，流感病毒对中枢神经系统细胞具有破坏作用。
