Winkler P A, Guyuron B
Division of Plastic Surgery, Mount Sinai Medical Center, Cleveland, Ohio.
Br J Plast Surg. 1987 Sep;40(5):528-31. doi: 10.1016/s0007-1226(87)90089-0.
A patient with basal cell naevus syndrome (Gorlin-Goltz Syndrome) is presented. Of note in the case was the extensive symmetrical tumour invasion of both external auditory canals requiring bilateral radical resection. The patient expired 14 months later, at which time the autopsy revealed widespread metastases to the pleura, diaphragm, pericardium, epicardium and myocardium. Although lung metastases have been reported in this syndrome, no cases have been reported of metastases to these sites.
本文报告了一例基底细胞痣综合征（Gorlin-Goltz综合征）患者。该病例值得注意的是，双侧外耳道均出现广泛对称性肿瘤浸润，需要进行双侧根治性切除。患者于14个月后死亡，尸检发现胸膜、膈肌、心包、心外膜和心肌均有广泛转移。虽然该综合征已有肺转移的报道，但尚无转移至这些部位的病例报告。
