Suppr超能文献

北欧国家半个世纪以来结肠癌、直肠癌和小肠癌的生存率

Survival in Colon, Rectal and Small Intestinal Cancers in the Nordic Countries through a Half Century.

作者信息

Tichanek Filip, Försti Asta, Liska Vaclav, Hemminki Akseli, Hemminki Kari

机构信息

Biomedical Center, Faculty of Medicine, Charles University Pilsen, 30605 Pilsen, Czech Republic.

Institute of Pathological Physiology, Faculty of Medicine in Pilsen, Charles University, 32300 Pilsen, Czech Republic.

出版信息

Cancers (Basel). 2023 Feb 3;15(3):991. doi: 10.3390/cancers15030991.

Abstract

Survival studies in intestinal cancers have generally shown favorable development, but few studies have been able to pinpoint the timing of the changes in survival over an extended period. Here, we compared the relative survival rates for colon, rectal and small intestinal cancers from Denmark (DK), Finland (FI), Norway (NO) and Sweden (SE). Relative 1-, 5- and 5/1-year conditional survival data were obtained from the NORDCAN database for the years 1971-2020. The 50-year survival patterns were country-specific. For colon and rectal cancers, the slopes of survival curves bended upwards for DK, were almost linear for NO and bended downwards for FI and SE; 5-year survival was the highest in DK. Survival in small intestinal cancer was initially below colon and rectal cancers but in FI and NO it caught up toward the end of the follow-up. Relative survival in intestinal cancers has developed well in the Nordic countries, and DK is an example of a country which in 20 years was able to achieve excellent survival rates in colon and rectal cancers. In the other countries, the increase in survival curves for colon and rectal cancer has slowed down, which may be a challenge posed by metastatic cancers.

摘要

肠道癌的生存研究总体显示出良好的发展态势,但很少有研究能够确定长期生存变化的时间点。在此,我们比较了丹麦(DK)、芬兰(FI)、挪威(NO)和瑞典(SE)结肠癌、直肠癌和小肠癌的相对生存率。1年、5年和5/1年的相对条件生存数据来自1971 - 2020年的NORDCAN数据库。50年的生存模式因国家而异。对于结肠癌和直肠癌,丹麦的生存曲线斜率向上弯曲,挪威几乎呈线性,芬兰和瑞典则向下弯曲;丹麦的5年生存率最高。小肠癌的生存率最初低于结肠癌和直肠癌,但在芬兰和挪威,在随访末期赶上了它们。北欧国家肠道癌的相对生存率发展良好,丹麦是一个在20年内能够在结肠癌和直肠癌方面实现优异生存率的国家的例子。在其他国家,结肠癌和直肠癌生存曲线的增长已经放缓,这可能是转移性癌症带来的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcd0/9913304/faa22d963121/cancers-15-00991-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验