Lovett L M, Shaw D M
Department of Psychological Medicine, University of Wales College of Medicine, Whitchurch Hospital, Cardiff.
Br J Psychiatry. 1987 Jul;151:113-6. doi: 10.1192/bjp.151.1.113.
Nine patients have been treated by subcaudate stereotactic tractotomy for bipolar affective disorder resistant to drug treatments. In the majority, after the operation there was a reduction in frequency and severity of depressive and manic episodes. There was a trend for the operation to have more effect on the manic than on the depressive phases. Drugs which had been inert previously sometimes became therapeutically useful after surgery.
九名患有对药物治疗耐药的双相情感障碍患者接受了尾状核下立体定向束切断术治疗。大多数患者术后抑郁和躁狂发作的频率及严重程度有所降低。手术对躁狂期的影响似乎比对抑郁期的影响更大。以前无效的药物术后有时会变得有治疗作用。
