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探讨自噬、调控性细胞死亡与细胞命运通路在癌症发病机制和治疗中的复杂关系。

Exploring the Complex Link between Autophagy, Regulated Cell Death, and Cell Fate Pathways in Cancer Pathogenesis and Therapy.

机构信息

Department of Molecular Medicine, Institute of Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran P.O. Box 14965/161, Iran.

Centre de Recherche des Cordeliers, INSERM UMRS 1138, Sorbonne Université, Université de Paris, Equipe 11 Labellisée par la Ligue Contre le Cancer, 75006 Paris, France.

出版信息

Cells. 2023 Feb 3;12(3):498. doi: 10.3390/cells12030498.

Abstract

Autophagy is a catabolic lysosomal-dependent pathway involved in the degradation of cellular materials, supplying precursor compounds and energy for macromolecule synthesis and metabolic needs [...].

摘要

自噬是一种溶酶体依赖性的分解代谢途径,参与细胞物质的降解,为大分子合成和代谢需求提供前体化合物和能量[... ]。

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