Altobelli Emma, Angeletti Paolo Matteo, Farello Giovanni, Petrocelli Reimondo
Department of Life, Public Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Cardiac Surgical Intensive Care Unit, Giuseppe Mazzini Hospital, 64100 Teramo, Italy.
Healthcare (Basel). 2023 Jan 17;11(3):283. doi: 10.3390/healthcare11030283.
The COVID-19 pandemic has dramatically affected all aspects of the patient's pathway to cancer diagnosis and subsequent treatment. Our main objective was to evaluate the status of cancer trials in Ukraine as of September 2022.
Initially, we examined with a narrative review the state of breast, colorectal, and cervical cancer population-based screening. Subsequently, we assessed each trial status for the years 2021 and 2022.
Estimates of participation in breast and cervical cancer screening are different from region to region. Moreover, regarding cervical cancer screening, extremely different participation estimates were reported: 73% in 2003 vs. <10% 2020. Our data show that from 2014 to 2020, despite the pandemic, cancer trials in Ukraine significantly increased from 27 to 44. In 2021 no trials were completed; in fact, we observed that out of 41 trials, 8 were active not recruiting, 33 were recruiting, and 0 were completed or terminated. In 2022 in Ukraine, for oncological pathologies, only 3 trials were registered, while in 2021, 41 trials were registered. The suspension of trials regarded above all concern hematological tissue (66.7%) and the genitourinary tract (60%).
Our work has highlighted how the areas most affected by the conflict present criticalities in oncological care.
新冠疫情对患者癌症诊断及后续治疗的各个环节都产生了巨大影响。我们的主要目标是评估截至2022年9月乌克兰癌症试验的状况。
首先，我们通过叙述性综述研究了基于人群的乳腺癌、结直肠癌和宫颈癌筛查状况。随后，我们评估了2021年和2022年各项试验的状态。
乳腺癌和宫颈癌筛查的参与率在不同地区有所不同。此外，关于宫颈癌筛查，报告的参与率差异极大：2003年为73%，而2020年则低于10%。我们的数据显示，从2014年到2020年，尽管疫情肆虐，乌克兰的癌症试验仍从27项显著增加至44项。2021年没有试验完成；事实上，我们观察到在41项试验中，8项处于活跃但未招募状态，33项正在招募，0项已完成或终止。2022年在乌克兰，针对肿瘤疾病，仅登记了3项试验，而2021年登记了41项试验。试验暂停主要涉及血液组织（66.7%）和泌尿生殖道（60%）。
我们的工作突出了受冲突影响最严重的地区在肿瘤护理方面存在的关键问题。
