Department Biomedical Sciences for Health, University of Milan, 20122 Milan, Italy.
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.
Int J Environ Res Public Health. 2023 Jan 17;20(3):1700. doi: 10.3390/ijerph20031700.
Blood transfusion can be considered as a life-saving treatment and is a primary health management topic. This study aims to assess the appropriateness of blood transfusion performed in a large tertiary hospital in Italy.
a multispecialist team composed oof hematologists, public health experts and pediatricians analyzed blood transfusions performed between 2018 and 2022 in the pediatric wards comparing the appropriateness with the available NHS guidelines available. Patients' characteristics, clinical features and blood component's data were collected and analyzed.
considering 147 blood transfusions performed in 2018-2022, only eight (5.4%) were performed according to guidelines, while 98 (66.7%) were driven by clinicians' expertise, especially for anemia in genetic syndromes (30) (20.5%) and autoimmune diseases (20) (13.6%). Thirty-nine (26.5%) transfusions could be considered as inappropriate, while two (1.4%) blood packs were never been transfused after being requested.
This analysis is one of the first performed to assess the appropriateness of blood component transfusions comparing their compliance to NHS guidelines. The importance of this analysis can be explained first by the clinical point of view and second by the economic one.
输血可以被视为一种救生治疗，是初级卫生管理的一个主要课题。本研究旨在评估意大利一家大型三级医院进行的输血的适宜性。
由血液学家、公共卫生专家和儿科医生组成的多学科团队分析了 2018 年至 2022 年在儿科病房进行的输血，将适宜性与现有的 NH S 指南进行比较。收集并分析了患者的特征、临床特征和血液成分数据。
考虑到 2018-2022 年进行的 147 次输血，只有 8 次（5.4%）符合指南，而 98 次（66.7%）是根据临床医生的专业知识进行的，特别是在遗传性综合征（30）（20.5%）和自身免疫性疾病（20）（13.6%）中出现贫血时。39 次（26.5%）输血可能被认为是不适当的，而有两袋（1.4%）血液在要求后从未输注过。
这是首次根据 NH S 指南评估血液成分输血的适宜性并对其进行比较的分析之一。这种分析的重要性可以从临床角度和经济角度来解释。
