Sharif Mumtaz, Saxena Amit, Singh Swati, Manchala Sundeep, Jafri Neha
Department of Pediatrics, D.Y. Patil Medical College, Nerul, Navi Mumbai, 400706, India.
Indian J Pediatr. 2020 May;87(5):339-344. doi: 10.1007/s12098-020-03186-2. Epub 2020 Mar 12.
To study the rational use of the blood components in pediatric and neonatal wards.
It was a retrospective study conducted by department of pediatrics of a tertiary care centre in western part of India. The patients were included from the pediatric ward, pediatric surgery ward, neonatal intensive care unit (NICU), pediatric intensive care unit (PICU) over a period of three months. All the patients below 12 y of age receiving blood components, admitted in general pediatric wards, pediatric intensive care unit, neonatal intensive care unit and pediatric surgery ward were included in the study. Each transfusion episode was assessed as per predetermined guidelines.
Of the total 336 episodes of blood component transfusions, 244 episodes were appropriate and 92 episodes were inappropriate. Among these, platelets had highest inappropriate (36.84%) episodes followed by fresh frozen plasma (FFP) (28.95%) and packed red blood cell transfusions (PRBC) (21.21%). Majority inappropriate transfusions were seen in intensive care settings.
Almost one-third of blood component transfusions (FFP, platelets and PRBC) were given without any definitive indication. Judicious use of various blood products by following recommended guidelines may help in decreasing the inappropriate use of blood components.
研究儿科和新生儿病房血液成分的合理使用情况。
这是一项由印度西部一家三级医疗中心的儿科进行的回顾性研究。研究对象包括三个月期间儿科病房、小儿外科病房、新生儿重症监护病房（NICU）、儿科重症监护病房（PICU）的患者。纳入研究的患者为年龄在12岁以下、在普通儿科病房、儿科重症监护病房、新生儿重症监护病房和小儿外科病房接受血液成分治疗的所有患者。每一次输血事件均按照预先确定的指南进行评估。
在总共336次血液成分输血事件中，244次是恰当的，92次是不恰当的。其中，血小板的不恰当输血事件发生率最高（36.84%），其次是新鲜冰冻血浆（FFP）（28.95%）和红细胞悬液输血（PRBC）（21.21%）。大多数不恰当输血事件发生在重症监护环境中。
几乎三分之一的血液成分输血（FFP、血小板和PRBC）在没有任何明确指征的情况下进行。遵循推荐指南明智地使用各种血液制品可能有助于减少血液成分的不恰当使用。
