Interventional Endoscopy, Foundation IRCCS San Gerardo dei Tintori, 20900 Monza, Italy.
Department of Surgery and Translational Medicine, Foundation IRCCS San Gerardo dei Tintori, University of Milano-Bicocca, 20900 Monza, Italy.
Int J Environ Res Public Health. 2023 Jan 25;20(3):2149. doi: 10.3390/ijerph20032149.
Gastric cancer (GC) is a relevant public health issue as its incidence and mortality rates are growing worldwide. There are recognized carcinogen agents, such as obesity, tobacco, meat, alcohol consumption and some dietary protective factors. Strategies of early diagnosis through population-based surveillance programs have been demonstrated to be effective in lowering the morbidity and mortality related to GC in some countries. Indeed, the detection of early lesions is very important in order to offer minimally invasive treatments. Endoscopic resection is the gold standard for lesions with a low risk of lymph node metastasis, whereas surgical mini-invasive approaches can be considered in early lesions when endoscopy is not curative. This review outlines the role of lifestyle and prevention strategies for GC, in order to reduce the patients' risk factors, implement the surveillance of precancerous conditions and, therefore, improve the diagnosis of early lesions. Furthermore, we summarize the available treatments for early gastric cancer.
胃癌(GC)是一个重要的公共卫生问题,因为其发病率和死亡率在全球范围内都在上升。已经有公认的致癌因素,如肥胖、烟草、肉类、酒精摄入和一些饮食保护因素。通过基于人群的监测计划进行早期诊断的策略已被证明在一些国家降低与 GC 相关的发病率和死亡率方面是有效的。事实上,早期发现病变非常重要,以便提供微创治疗。内镜下切除是低淋巴结转移风险病变的金标准,而对于内镜治疗无法治愈的早期病变,可以考虑采用微创手术方法。这篇综述概述了生活方式和预防策略在 GC 中的作用,以降低患者的危险因素,实施癌前病变的监测,从而改善早期病变的诊断。此外,我们还总结了早期胃癌的治疗方法。