• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

肥厚型心肌病的遗传和分子机制。

Genetic and Molecular Mechanisms of Hypertrophic Cardiomyopathy.

机构信息

Department of Medicine, Tufts University School of Medicine, Boston, MA 02111, USA.

Molecular Cardiology Research Institute, Tufts Medical Center, Boston, MA 02111, USA.

出版信息

Int J Mol Sci. 2023 Jan 28;24(3):2522. doi: 10.3390/ijms24032522.

DOI:10.3390/ijms24032522
PMID:36768840
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9916656/
Abstract

The intention of this Special Issue is to highlight novel approaches and new paradigms for understanding the pathogenesis of hypertrophic cardiomyopathy (HCM) [...].

摘要

本特刊的目的是强调理解肥厚型心肌病（HCM）发病机制的新方法和新范式[... ]。

相似文献

1
Genetic and Molecular Mechanisms of Hypertrophic Cardiomyopathy.肥厚型心肌病的遗传和分子机制。
Int J Mol Sci. 2023 Jan 28;24(3):2522. doi: 10.3390/ijms24032522.
2
[Advances in the molecular pathogenesis of hypertrophic cardiomyopathy].肥厚型心肌病的分子发病机制研究进展
Yi Chuan. 2011 Jun;33(6):549-57. doi: 10.3724/sp.j.1005.2011.00549.
3
Posterolateral hypertrophic cardiomyopathy: a rare, but clinically significant variant of hypertrophic cardiomyopathy. Posterolateral 肥厚型心肌病：肥厚型心肌病的一种罕见但具有临床意义的变体。
Cardiovasc Pathol. 2014 Nov-Dec;23(6):381-2. doi: 10.1016/j.carpath.2014.07.002. Epub 2014 Jul 15.
4
Molecular analysis of sarcomeric and non-sarcomeric genes in patients with hypertrophic cardiomyopathy.肥厚型心肌病患者肌节和非肌节基因的分子分析。
Gene. 2016 Feb 15;577(2):227-35. doi: 10.1016/j.gene.2015.11.048. Epub 2015 Dec 2.
5
Pathogenic Mechanisms of Hypertrophic Cardiomyopathy beyond Sarcomere Dysfunction.肥厚型心肌病的致病机制远不止于肌节功能障碍。
Int J Mol Sci. 2021 Aug 19;22(16):8933. doi: 10.3390/ijms22168933.
6
Hypertrophic cardiomyopathy: part 1 - introduction, pathology and pathophysiology.肥厚型心肌病：第1部分——引言、病理学和病理生理学。
Ann Card Anaesth. 2014 Apr-Jun;17(2):118-24. doi: 10.4103/0971-9784.129841.
7
Hypertrophic cardiomyopathy in man and cats.人类和猫的肥厚型心肌病。
J Vet Cardiol. 2015 Dec;17 Suppl 1:S6-9. doi: 10.1016/j.jvc.2015.03.007.
8
Hypertrophic cardiomyopathy: current understanding and treatment objectives.肥厚型心肌病：当前的认识与治疗目标
J Clin Pathol. 2009 Mar;62(3):226-35. doi: 10.1136/jcp.2008.061655. Epub 2008 Oct 17.
9
TGFβ-inducible early gene-1 (TIEG1) mutations in hypertrophic cardiomyopathy.TGFβ 诱导早期基因 1（TIEG1）突变与肥厚型心肌病。
J Cell Biochem. 2012 Jun;113(6):1896-903. doi: 10.1002/jcb.24058.
10
The clinical features, outcomes and genetic characteristics of hypertrophic cardiomyopathy patients with severe right ventricular hypertrophy.伴有严重右心室肥厚的肥厚型心肌病患者的临床特征、预后及遗传学特征
PLoS One. 2017 Mar 21;12(3):e0174118. doi: 10.1371/journal.pone.0174118. eCollection 2017.

引用本文的文献

1
Hypertrophic cardiomyopathy occurred after successful surgical correction of supravalvular aortic stenosis: a case report of Williams-Beuren syndrome.主动脉瓣上狭窄成功手术矫正后发生肥厚型心肌病：威廉姆斯-贝伦综合征病例报告
Front Pediatr. 2025 Aug 8;13:1580272. doi: 10.3389/fped.2025.1580272. eCollection 2025.
2
The Key Role and Mechanism of Oxidative Stress in Hypertrophic Cardiomyopathy: A Systematic Exploration Based on Multi-Omics Analysis and Experimental Validation.氧化应激在肥厚型心肌病中的关键作用及机制：基于多组学分析和实验验证的系统探索
Antioxidants (Basel). 2025 May 7;14(5):557. doi: 10.3390/antiox14050557.
3
Genetic Mutations and Mitochondrial Redox Signaling as Modulating Factors in Hypertrophic Cardiomyopathy: A Scoping Review.遗传突变与线粒体氧化还原信号在肥厚型心肌病中的调节作用：系统评价
Int J Mol Sci. 2024 May 28;25(11):5855. doi: 10.3390/ijms25115855.

本文引用的文献

1
Common and Distinctive Intercellular Communication Patterns in Human Obstructive and Nonobstructive Hypertrophic Cardiomyopathy.人类梗阻性和非梗阻性肥厚型心肌病中常见和独特的细胞间通讯模式。
Int J Mol Sci. 2022 Jan 15;23(2):946. doi: 10.3390/ijms23020946.
2
Mass-Spectrometry-Based Functional Proteomic and Phosphoproteomic Technologies and Their Application for Analyzing Ex Vivo and In Vitro Models of Hypertrophic Cardiomyopathy.基于质谱的功能蛋白质组学和磷酸化蛋白质组学技术及其在分析肥厚型心肌病体外和体内模型中的应用。
Int J Mol Sci. 2021 Dec 20;22(24):13644. doi: 10.3390/ijms222413644.
3
Genetic Testing in Patients with Hypertrophic Cardiomyopathy.肥厚型心肌病患者的基因检测。
Int J Mol Sci. 2021 Sep 27;22(19):10401. doi: 10.3390/ijms221910401.
4
Pathogenic Mechanisms of Hypertrophic Cardiomyopathy beyond Sarcomere Dysfunction.肥厚型心肌病的致病机制远不止于肌节功能障碍。
Int J Mol Sci. 2021 Aug 19;22(16):8933. doi: 10.3390/ijms22168933.
5
Electrophysiological and Structural Remodeling of the Atria in a Mouse Model of Troponin-I Mutation Linked Hypertrophic Cardiomyopathy: Implications for Atrial Fibrillation.肌钙蛋白 I 突变相关肥厚型心肌病小鼠模型中心房的电生理和结构重构：对心房颤动的影响。
Int J Mol Sci. 2021 Jun 28;22(13):6941. doi: 10.3390/ijms22136941.
6
Plasma Proteomic Profiling in Hypertrophic Cardiomyopathy Patients before and after Surgical Myectomy Reveals Post-Procedural Reduction in Systemic Inflammation.肥厚型心肌病患者手术心肌切除术前后的血浆蛋白质组学分析显示术后全身性炎症减少。
Int J Mol Sci. 2021 Mar 1;22(5):2474. doi: 10.3390/ijms22052474.