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阿达木单抗对化脓性汗腺炎患者抗生素处方的影响:一项为期1年的前瞻性研究和回顾性分析。

How Adalimumab Impacts Antibiotic Prescriptions in Patients Affected by Hidradenitis Suppurativa: A 1-Year Prospective Study and Retrospective Analysis.

作者信息

Martora Fabrizio, Marasca Claudio, Picone Vincenzo, Fornaro Luigi, Megna Matteo, Fabbrocini Gabriella

机构信息

Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, 80138 Napoli, Italy.

Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione "G. Pascale", 80131 Napoli, Italy.

出版信息

J Clin Med. 2023 Jan 20;12(3):837. doi: 10.3390/jcm12030837.

Abstract

We conducted a one-year prospective study involving the enrollment of 58 patients with Hidradenitis Suppurativa. Through a retrospective analysis of data on the same patients, with reference to the year prior to the initiation of the anti-TNFα drug adalimumab, we aimed to show how the advent of this biologic therapy changes the number of days of antibiotic therapy, the number of flare-ups per year, and their duration in days, as well as the quality of life and perceived pain of patients.

摘要

我们开展了一项为期一年的前瞻性研究,纳入了58例化脓性汗腺炎患者。通过对同一批患者的数据进行回顾性分析,并参考抗TNFα药物阿达木单抗治疗开始前一年的情况,我们旨在展示这种生物疗法的出现如何改变抗生素治疗天数、每年的病情发作次数及其持续天数,以及患者的生活质量和疼痛感受。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc7e/9917487/b7a20f199e35/jcm-12-00837-g001.jpg

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