Coffeng Sophie M, Foks Kelly A, van den Brand Crispijn L, Jellema Korné, Dippel Diederik W J, Jacobs Bram, van der Naalt Joukje
Department of Emergency Medicine, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Department of Neurology, Erasmus MC University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands.
J Clin Med. 2023 Jan 27;12(3):982. doi: 10.3390/jcm12030982.
Age is variably described as a minor or major risk factor for traumatic intracranial lesions after head injury. However, at present, no specific CT decision rule is available for elderly patients with minor head injury (MHI). The aims of this prospective multicenter cohort study were to assess the performance of existing CT decision rules for elderly MHI patients and to compare the clinical and CT characteristics of elderly patients with the younger MHI population. Thirty-day mortality between two age groups (cutoff ≥ 60 years), along with clinical and CT characteristics, was evaluated with four CT decision rules: the National Institute for Health and Care Excellence (NICE) guideline, the Canadian CT Head Rule (CCHR), the New Orleans Criteria (NOC), and the CT Head Injury Patients (CHIP) rule. Of the 5517 MHI patients included, 2310 were aged ≥ 60 years. Elderly patients experienced loss of consciousness (17% vs. 32%) and posttraumatic amnesia (23% vs. 31%) less often, but intracranial lesions (13% vs. 10%), neurological deterioration (1.8% vs. 0.2%), and 30-day mortality (2.0% vs. 0.1%) were more frequent than in younger patients (all < 0.001). Elderly patients with age as their only risk factor showed intracranial lesions in 5% (NOC and CHIP) to 8% (CCHR and NICE) of cases. The sensitivity of decision rules in the elderly patients was 60% (CCHR) to 97% (NOC) when age was excluded as a risk factor. Current risk factors considered when evaluating elderly patients show lower sensitivity to identify intracranial abnormalities, despite more frequent intracranial lesions. Until age-specific CT decision rules are developed, it is advisable to scan every elderly patient with an MHI.
年龄被不同程度地描述为头部受伤后创伤性颅内病变的次要或主要风险因素。然而,目前尚无针对轻度头部损伤(MHI)老年患者的具体CT决策规则。这项前瞻性多中心队列研究的目的是评估现有CT决策规则对老年MHI患者的适用性,并比较老年患者与年轻MHI人群的临床和CT特征。采用四项CT决策规则,即英国国家卫生与临床优化研究所(NICE)指南、加拿大CT头部规则(CCHR)、新奥尔良标准(NOC)和CT头部损伤患者(CHIP)规则,评估两个年龄组(分界值≥60岁)之间的30天死亡率以及临床和CT特征。在纳入的5517例MHI患者中,2310例年龄≥60岁。老年患者意识丧失(17%对32%)和创伤后遗忘(23%对31%)的发生率较低,但颅内病变(13%对10%)、神经功能恶化(1.8%对0.2%)和30天死亡率(2.0%对0.1%)比年轻患者更常见(均P<0.001)。仅以年龄为唯一风险因素的老年患者中,5%(NOC和CHIP)至8%(CCHR和NICE)的病例出现颅内病变。当排除年龄作为风险因素时,决策规则在老年患者中的敏感性为60%(CCHR)至97%(NOC)。尽管老年患者颅内病变更常见,但目前评估老年患者时所考虑的风险因素对识别颅内异常的敏感性较低。在制定针对特定年龄的CT决策规则之前,建议对每例老年MHI患者进行扫描。