Influence of InP/ZnS Quantum Dots on Thermodynamic Properties and Morphology of the DPPC/DPPG Monolayers at Different Temperatures.

In this work, the effects of InP/ZnS quantum dots modified with amino or carboxyl group on the characteristic parameters in phase behavior, elastic modulus, relaxation time of the DPPC/DPPG mixed monolayers are studied by the Langmuir technology at the temperature of 37, 40 and 45 °C. Additionally, the information on the morphology and height of monolayers are obtained by the Langmuir-Bloggett technique and atomic force microscope technique. The results suggest that the modification of the groups can reduce the compressibility of monolayers at a higher temperature, and the most significant effect is the role of the amino group. At a high temperature of 45 °C, the penetration ability of InP/ZnS-NH quantum dots in the LC phase of the mixed monolayer is stronger. At 37 °C and 40 °C, there is no clear difference between the penetration ability of InP/ZnS-NH quantum dots and InP/ZnS-COOH quantum dots. The InP/ZnS-NH quantum dots can prolong the recombination of monolayers at 45 °C and accelerate it at 37 °C and 40 °C either in the LE phase or in the LC phase. However, the InP/ZnS-COOH quantum dots can accelerate it in the LE phase at all temperatures involved but only prolong it at 45 °C in the LC phase. This work provides support for understanding the effects of InP/ZnS nanoparticles on the structure and properties of cell membranes, which is useful for understanding the behavior about the ingestion of nanoparticles by cells and the cause of toxicity.