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肺移植受者的重症监护管理。

Critical Care Management of the Lung Transplant Recipient.

机构信息

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, New York University Grossman School of Medicine, 530 First Avenue, HCC 4A, New York, NY 10016, USA.

Division of Pulmonary, Allergy, and Critical Care, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Hospital of the University of Pennsylvania, 3400 Spruce Street, 9036 Gates Building, Philadelphia, PA 19104, USA.

出版信息

Clin Chest Med. 2023 Mar;44(1):105-119. doi: 10.1016/j.ccm.2022.10.010.

DOI:10.1016/j.ccm.2022.10.010
PMID:36774158
Abstract

Lung transplantation is often the only treatment option for patients with severe irreversible lung disease. Improvements in donor and recipient selection, organ allocation, surgical techniques, and immunosuppression have all contributed to better survival outcomes after lung transplantation. Nonetheless, lung transplant recipients still experience frequent complications, often necessitating treatment in an intensive care setting. In addition, the use of extracorporeal life support as a means of bridging critically ill patients to lung transplantation has become more widespread. This review focuses on the critical care aspects of lung transplantation, both before and after surgery.

摘要

肺移植通常是严重不可逆肺疾病患者的唯一治疗选择。供体和受体选择、器官分配、手术技术和免疫抑制方面的改进都有助于提高肺移植后的生存结果。尽管如此,肺移植受者仍经常发生并发症,往往需要在重症监护环境中进行治疗。此外,体外生命支持作为将危重病患者桥接至肺移植的手段已变得更为广泛。这篇综述重点介绍了肺移植手术前后的重症护理方面。

相似文献

1
Critical Care Management of the Lung Transplant Recipient.肺移植受者的重症监护管理。
Clin Chest Med. 2023 Mar;44(1):105-119. doi: 10.1016/j.ccm.2022.10.010.
2
Lung transplantation: donor and recipient critical care aspects.
Curr Opin Crit Care. 2005 Aug;11(4):339-44. doi: 10.1097/01.ccx.0000170507.55443.90.
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Mechanical Ventilation and Extracorporeal Membrane Oxygenation as a Bridging Strategy to Lung Transplantation: Significant Gains in Survival.机械通气和体外膜肺氧合作为肺移植桥接策略:显著提高生存率。
Am J Transplant. 2018 Jan;18(1):125-135. doi: 10.1111/ajt.14422. Epub 2017 Aug 29.
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An observational study of Donor Ex Vivo Lung Perfusion in UK lung transplantation: DEVELOP-UK.英国肺移植中供体体外肺灌注的观察性研究:DEVELOP-UK。
Health Technol Assess. 2016 Nov;20(85):1-276. doi: 10.3310/hta20850.
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Continued Successful Evolution of Extended Criteria Donor Lungs for Transplantation.用于移植的扩大标准供体肺的持续成功演变。
Ann Thorac Surg. 2017 Nov;104(5):1702-1709. doi: 10.1016/j.athoracsur.2017.05.042. Epub 2017 Sep 28.
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Extended criteria donor lungs do not impact recipient outcomes in pediatric transplantation.扩展标准供体肺不影响儿科移植受者的结局。
J Heart Lung Transplant. 2019 May;38(5):560-569. doi: 10.1016/j.healun.2019.02.012. Epub 2019 Feb 27.
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Early airway dehiscence: Risk factors and outcomes with the rising incidence of extracorporeal membrane oxygenation as a bridge to lung transplantation.早期气道裂开:随着体外膜肺氧合作为肺移植桥梁的应用日益增多,其危险因素及结局
J Card Surg. 2019 Oct;34(10):933-940. doi: 10.1111/jocs.14157. Epub 2019 Jul 23.
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Induction type and outcomes for kidney graft and patient survival in recipients with prior lung transplantation in the United States.美国既往接受过肺移植的肾移植受者的肾移植诱导类型及肾移植和患者生存结局
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Extracorporeal membrane oxygenation as a bridge to lung transplantation: A single-center experience in the present era.体外膜肺氧合作为肺移植的桥梁:当前时代的单中心经验。
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引用本文的文献

1
Donor lung weight a novel predictor for primary graft dysfunction.供体肺重量:原发性移植肺功能障碍的一种新型预测指标。
JHLT Open. 2025 Apr 30;9:100271. doi: 10.1016/j.jhlto.2025.100271. eCollection 2025 Aug.
2
A novel nomogram for predicting prolonged mechanical ventilation in lung transplantation patients using extracorporeal membrane oxygenation.一种使用体外膜肺氧合预测肺移植患者机械通气时间延长的新型列线图。
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