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通过对话主义和实用主义支持的极早产出生的生物伦理决策。

Extremely premature birth bioethical decision-making supported by dialogics and pragmatism.

机构信息

Providence St. Vincent Medical Center, Women and Children's Services, 9205 SW Barnes Road, Portland, OR, 97225, USA.

Department of Obstetrics, Gynecology, and Newborn Care, The Ottawa Hospital - General Campus, 501 Smyth Road, Box 806, Ottawa, ON, K1H 8L6, Canada.

出版信息

BMC Med Ethics. 2023 Feb 11;24(1):9. doi: 10.1186/s12910-023-00887-z.

DOI:10.1186/s12910-023-00887-z
PMID:36774482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9922460/
Abstract

Moral values in healthcare range widely between interest groups and are principally subjective. Disagreements diminish dialogue and marginalize alternative viewpoints. Extremely premature births exemplify how discord becomes unproductive when conflicts of interest, cultural misunderstanding, constrained evidence review, and peculiar hierarchy compete without the balance of objective standards of reason. Accepting uncertainty, distributing risk fairly, and humbly acknowledging therapeutic limits are honorable traits, not relativism, and especially crucial in our world of constrained resources. We think dialogics engender a mutual understanding that: i) transitions beliefs beyond bias, ii) moves conflict toward pragmatism (i.e., the truth of any position is verified by subsequent experience), and iii) recognizes value pluralism (i.e., human values are irreducibly diverse, conflicting, and ultimately incommensurable). This article provides a clear and useful Point-Counterpoint of extreme prematurity controversies, an objective neurodevelopmental outcomes table, and a dialogics exemplar to cultivate shared empathetic comprehension, not to create sides from which to choose. It is our goal to bridge the understanding gap within and between physicians and bioethicists. Dialogics accept competing relational interests as human nature, recognizing that ultimate solutions satisfactory to all are illusory, because every choice has downside. Nurturing a collective consciousness via dialogics and pragmatism is congenial to integrating objective evidence review and subjective moral-cultural sentiments, and is that rarest of ethical constructs, a means and an end.

摘要

医疗保健中的道德价值观在利益群体之间差异很大,主要是主观的。分歧会减少对话,并使替代观点边缘化。早产儿的例子说明了当利益冲突、文化误解、有限的证据审查以及特殊的等级制度在没有客观理性标准平衡的情况下相互竞争时,不和谐会变得没有成效。接受不确定性、公平分配风险以及谦逊地承认治疗限制是值得尊敬的品质,而不是相对主义,尤其是在我们资源有限的世界中更为关键。我们认为对话论可以产生相互理解,即:i)超越偏见转变信念,ii)使冲突走向实用主义(即任何立场的真理都可以通过后续经验来验证),iii)认识到价值多元化(即人类价值观是不可还原的、冲突的,最终是不可通约的)。本文提供了一个关于极端早产争议的清晰而有用的观点对比,一个客观的神经发育结果表,以及一个对话论的范例,以培养共同的同理心理解,而不是制造选择的对立面。我们的目标是弥合医生和生物伦理学家之间的理解差距。对话论接受相互竞争的关系利益作为人性,认识到最终让所有人都满意的解决方案是虚幻的,因为每个选择都有缺点。通过对话论和实用主义培养集体意识,有利于整合客观的证据审查和主观的道德文化观念,这是最罕见的伦理结构之一,既是手段也是目的。

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Change in neurodevelopmental outcomes for extremely premature infants over time: a systematic review and meta-analysis.随着时间的推移,极早产儿神经发育结局的变化:系统评价和荟萃分析。
Arch Dis Child Fetal Neonatal Ed. 2023 Sep;108(5):458-463. doi: 10.1136/archdischild-2022-324457. Epub 2022 Oct 21.
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Health-Related Quality of Life from Adolescence to Adulthood Following Extremely Preterm Birth.极早产儿成年后与健康相关的生活质量。
J Pediatr. 2021 Oct;237:227-236.e5. doi: 10.1016/j.jpeds.2021.04.005. Epub 2021 Apr 7.
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The Edge of Perinatal Viability: Understanding the Dutch Position.围产期生存能力的边缘:理解荷兰的立场。
Front Pediatr. 2021 Feb 1;9:634290. doi: 10.3389/fped.2021.634290. eCollection 2021.
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Unbiasing costs? An appraisal of economic assessment alongside randomized trials in neonatology.消除偏倚的代价?新生儿学中随机试验与经济评估的再评价。
Semin Perinatol. 2021 Apr;45(3):151391. doi: 10.1016/j.semperi.2021.151391. Epub 2021 Jan 24.
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Preterm birth lifetime costs in the United States in 2016: An update.2016 年美国早产儿终生成本:更新。
Semin Perinatol. 2021 Apr;45(3):151390. doi: 10.1016/j.semperi.2021.151390. Epub 2021 Jan 24.
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Sleep softly: Schubert, ethics and the value of dying well.安然入眠:舒伯特、伦理学与善终的价值
J Med Ethics. 2020 Nov 27;47(4):218-24. doi: 10.1136/medethics-2020-106937.
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Effect of Neonatal Outcome Estimates on Decision-Making Preferences of Mothers Facing Preterm Birth: A Randomized Clinical Trial.新生儿结局预测对面临早产的母亲决策偏好的影响:一项随机临床试验。
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Historical Perspectives: Shared Decision Making in the NICU.历史视角:NICU 中的共同决策。
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J Perinatol. 2020 Jul;40(7):1091-1099. doi: 10.1038/s41372-020-0635-z. Epub 2020 Feb 26.
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