镰状细胞病患儿的补充与替代医学：一项系统评价
Complementary and alternative medicine for children with sickle cell disease: A systematic review.
作者信息
Alsabri Mohammed, Carfagnini Christina, Amin Mody, Castilo Fiorella, Lewis Jeremy, Ashkar Mohammad, Hamzah Mohammed, Mohamed Nader, Saker Mohammed, Mahgerefteh Joseph, St Victor Rosemarie, Peichev Mario, Kupferman Fernanda, Viswanathan Kusum
机构信息
Pediatrics Department, One Brooklyn Health, Brookdale University Hospital Medical Center, 1 Brookdale Plaza, Brooklyn, New York 11212, USA.
Saba University School of Medicine, The Bottom, Saba, Caribbean Netherlands.
出版信息
Blood Rev. 2023 May;59:101052. doi: 10.1016/j.blre.2023.101052. Epub 2023 Jan 30.
BACKGROUND
Complementary and alternative medicine (CAM) is a popular alternative to opioid and other analgesics in sickle cell disease (SCD). We review the effectiveness, prevalence, and factors associated with CAM use in the pediatric SCD population.
METHODS
The review protocol was created based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. A literature search was conducted in MEDLINE, Embase, Cochrane Library, PubMed, and Web of Science.
RESULTS
Twenty-four studies were examined. The prevalence of CAM use in pediatric patients with SCD ranged from 36 to 84.5%. Common inpatient CAM interventions were yoga, virtual reality, and acupuncture, which decreased pain scale scores. Outpatient CAMs were consisted of cognitive behavioral therapy, massage therapy, and guided-imagery, which increased pain tolerability and decreased pain scale scores.
CONCLUSIONS
CAM modalities can decrease pain scale scores. However, the impact of specific CAM modalities on emergency department visits, hospitalizations, and school absences were inconclusive.
背景
补充和替代医学（CAM）是镰状细胞病（SCD）中替代阿片类药物和其他镇痛药的常用选择。我们回顾了儿科SCD人群中CAM使用的有效性、患病率及相关因素。
方法
根据系统评价和Meta分析的首选报告项目指南制定了综述方案。在MEDLINE、Embase、Cochrane图书馆、PubMed和科学网进行了文献检索。
结果
共审查了24项研究。儿科SCD患者中CAM的使用率在36%至84.5%之间。常见的住院CAM干预措施有瑜伽、虚拟现实和针灸，这些措施降低了疼痛量表评分。门诊CAM包括认知行为疗法、按摩疗法和引导想象，这些措施提高了疼痛耐受性并降低了疼痛量表评分。
结论
CAM方式可降低疼痛量表评分。然而，特定CAM方式对急诊就诊、住院和缺课的影响尚无定论。
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