根据体重指数调整后的低骨骼肌指数是炎症性肠病手术并发症的独立危险因素。
Low Skeletal Muscle Index Adjusted for Body Mass Index Is an Independent Risk Factor for Inflammatory Bowel Disease Surgical Complications.
作者信息
Berger Matthew, Yamada Akihiro, Komaki Yuga, Komaki Fukiko, Cohen Russell D, Dalal Sushila, Hurst Roger D, Hyman Neil, Pekow Joel, Shogan Benjamin D, Umanskiy Konstantin, Rubin David T, Sakuraba Atsushi, Micic Dejan
机构信息
Section of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, University of Chicago Medicine, Chicago, Illinois, USA.
Section of Gastroenterology, Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, Japan.
出版信息
Crohns Colitis 360. 2020 Aug 1;2(3):otaa064. doi: 10.1093/crocol/otaa064. eCollection 2020 Jul.
BACKGROUND
This study aims to evaluate sarcopenia defined by skeletal muscle index (SMI) with cutoffs adjusted for sex and body mass index as a predictive marker for postoperative outcomes among individuals with inflammatory bowel disease.
METHODS
The SMI was measured using the cross-sectional computed tomography images at the lumbar spine. Multivariate logistic regression was performed to identify independent risk factors of postoperative complications.
RESULTS
Ninety-one patients were included in the study. In multivariate analysis, sarcopenia (odds ratio = 5.37; confidence interval: 1.04-27.6) was predictive of infectious postoperative complications.
CONCLUSIONS
Sarcopenia as defined by the SMI is a predictor for 30-day postoperative infection complications in inflammatory bowel disease surgeries.
背景
本研究旨在评估通过骨骼肌指数（SMI）定义的肌肉减少症，并根据性别和体重指数调整临界值，将其作为炎症性肠病患者术后结局的预测指标。
方法
使用腰椎的横断面计算机断层扫描图像测量SMI。进行多因素逻辑回归以确定术后并发症的独立危险因素。
结果
91例患者纳入本研究。在多因素分析中，肌肉减少症（优势比=5.37；置信区间：1.04-27.6）可预测术后感染性并发症。
结论
由SMI定义的肌肉减少症是炎症性肠病手术中30天术后感染并发症的预测指标。
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