Godala Małgorzata, Gaszyńska Ewelina, Walczak Konrad, Małecka-Wojciesko Ewa
Department of Nutrition and Epidemiology, Medical University of Lodz, 90-752 Lodz, Poland.
Department of Internal Medicine and Nephrodiabetology, Medical University of Lodz, 90-549 Lodz, Poland.
Nutrients. 2025 Apr 17;17(8):1369. doi: 10.3390/nu17081369.
Methods used in daily clinical practice for the assessment of the nutritional status in patients with inflammatory bowel disease (IBD) are often based on simple indices and may not be sufficient in the case of minor or early changes. The purpose of this study was to analyze the nutritional status in patients with IBD.
The case-control study included 80 patients with IBD. The control group consisted of 80 healthy subjects matched based on age and gender. Body composition was measured using the electrical bioimpedance method.
Compared to the healthy women, the female patients with IBD had a significantly lower muscle mass (24.4 kg vs. 27.9 kg) and muscle strength (22.4 kg vs. 25.9 kg), as well as a lower MMI (7.8 kg/m vs. 9.9 kg/m). Based on these findings, sarcopenia was diagnosed in 37.5% of the female patients, significantly more often than in the control group. In the group of men, there were no significant differences between the healthy controls and patients in terms of body composition and the prevalence of underweight and sarcopenia.
The patients with IBD were characterized by a poorer nutritional status than the healthy subjects, mainly in terms of fat-free body mass and muscle mass, and consequently a higher incidence of sarcopenia, especially in the female group.
炎症性肠病（IBD）患者营养状况评估的日常临床实践中所使用的方法通常基于简单指标，对于轻微或早期变化可能并不充分。本研究的目的是分析IBD患者的营养状况。
病例对照研究纳入了80例IBD患者。对照组由80名基于年龄和性别匹配的健康受试者组成。使用生物电阻抗法测量身体成分。
与健康女性相比，IBD女性患者的肌肉量（24.4千克对27.9千克）和肌肉力量（22.4千克对25.9千克）显著更低，肌肉质量指数（MMI）也更低（7.8千克/米对9.9千克/米）。基于这些发现，37.5%的女性患者被诊断为肌肉减少症，明显高于对照组。在男性组中，健康对照组与患者在身体成分以及体重过轻和肌肉减少症患病率方面无显著差异。
IBD患者的营养状况比健康受试者差，主要体现在去脂体重和肌肉量方面，因此肌肉减少症的发生率更高，尤其是在女性组中。
