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伯利兹慢性肾脏病的患病率及危险因素:一项基于人群的调查。

Prevalence and Risk Factors for Chronic Kidney Disease in Belize: A Population-based Survey.

作者信息

Lin Jian-Jhang, Morey Francis, Wu Hon-Yen, Yang Ju-Yeh, Peng Yu-Sen, Mendez Deysi, Chebat Michel

机构信息

International Cooperation and Development Fund (TaiwanICDF), Taipei City, Taiwan.

Ministry of Health and Wellness, Belmopan, Belize.

出版信息

Lancet Reg Health Am. 2021 Jul 17;1:100013. doi: 10.1016/j.lana.2021.100013. eCollection 2021 Sep.

DOI:10.1016/j.lana.2021.100013
PMID:36776754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9903977/
Abstract

BACKGROUND

Health resources supporting dialysis and chronic kidney disease (CKD) patients are limited in Central America, and little information about the prevalence and risk factors for CKD in this region is available.

METHODS

The Survey of Risk Factors for Chronic Kidney Disease was a population-based cross-sectional study conducted throughout Belize in 2017. The study aimed to assess the prevalence and risk factors for CKD via structured questionnaires and clinical measurements in Belizeans aged 20-55 years. A two-stage stratified sampling technique was applied. CKD was defined as an estimated glomerular filtration rate < 60 mL/min/1·73 m or the presence of proteinuria.

FINDINGS

A total of 7,506 adults with a mean age of 34·6 years old completed the survey; 53·2% were women. The overall CKD prevalence was 13·7%. Women had a higher CKD prevalence than men (14·8% vs. 12·5%), and the overall awareness of CKD was low (3·7%). The prevalences of stage 1, 2, 3a, 3b, 4, and 5 CKD were 2·85%, 2·93%, 6·59%, 1·10%, 0·18%, and 0·06%, respectively. Older age, female sex, Mestizo/Hispanic ethnicity, diabetes, hypertension, hypercholesterolaemia, and obesity were identified as independent risk factors for CKD.

INTERPRETATION

The prevalence of CKD was 13·7% in Belizeans aged 20-55 years. The study confirms the high burden of CKD in Belize and provides important epidemiological information for Central America. Case management systems and surveillance programmes targeting high-risk populations are crucial for ameliorating the burden of CKD.

FUNDING

Capacity Building Project for the Prevention and Control of Chronic Renal Failure in Belize.

摘要

背景

中美洲用于支持透析和慢性肾脏病(CKD)患者的卫生资源有限,且该地区关于CKD患病率及危险因素的信息匮乏。

方法

慢性肾脏病危险因素调查是一项于2017年在伯利兹全国开展的基于人群的横断面研究。该研究旨在通过结构化问卷和临床测量评估20至55岁伯利兹人的CKD患病率及危险因素。采用了两阶段分层抽样技术。CKD定义为估算肾小球滤过率<60 mL/min/1·73 m²或存在蛋白尿。

研究结果

共有7506名平均年龄为34.6岁的成年人完成了调查;其中53.2%为女性。CKD总体患病率为13.7%。女性的CKD患病率高于男性(14.8%对12.5%),且CKD总体知晓率较低(3.7%)。1、2、3a、3b、4和5期CKD的患病率分别为2.85%、2.93%、6.59%、1.10%、0.18%和0.06%。年龄较大、女性、梅斯蒂索/西班牙裔种族、糖尿病、高血压、高胆固醇血症和肥胖被确定为CKD的独立危险因素。

解读

20至55岁伯利兹人的CKD患病率为13.7%。该研究证实了伯利兹CKD的高负担,并为中美洲提供了重要的流行病学信息。针对高危人群的病例管理系统和监测项目对于减轻CKD负担至关重要。

资金来源

伯利兹慢性肾衰竭预防与控制能力建设项目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3fe/9903977/756ebdd80eb2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3fe/9903977/756ebdd80eb2/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3fe/9903977/756ebdd80eb2/gr1.jpg

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