Department of Orthopedic Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.
Department of Orthopedic Surgery, Seoul National University Hospital, Seoul, Korea.
Clin Orthop Surg. 2023 Feb;15(1):145-152. doi: 10.4055/cios22099. Epub 2022 Aug 16.
Although pregnant or lactating women have been recognized to be predisposed to de Quervain's tenosynovitis (DQT), there is a lack of epidemiologic evidence. The purpose of this study was to estimate the nationwide incidence of pregnancy-related DQT (PRDQT) and to analyze risk factors using the Korean National Health Insurance (NHI) database.
A retrospective epidemiologic study of pregnant women in South Korea from 2013 to 2017 was conducted using the NHI claims database. Using corresponding diagnostic codes, we identified women diagnosed with DQT during pregnancy or the postpartum period. We calculated the cumulative incidence and analyzed risk factors such as demographics, pregnancy type, delivery method, gestational complications, and comorbidities using multivariate logistic regression analysis.
Between 2013 and 2017, 34,342 patients with PRDQT were identified among 1,601,501 pregnant women, representing a cumulative incidence of approximately 2.1%. Age ≥ 30 years, multiple gestation, cesarean delivery, hypertensive disorders in pregnancy, and underlying rheumatoid arthritis were all identified as significant risk factors for the occurrence of PRDQT, whereas diabetic disorders in pregnancy and underlying diabetes mellitus were not.
In South Korea, PRDQT was found to affect approximately 2.1 out of 100 pregnant women between 2013 and 2017. The incidence and risk factors identified in this study can be used for clinical consultations and prediction, as well as for development of national health policies.
尽管已经认识到孕妇或哺乳期妇女易患桡骨茎突狭窄性腱鞘炎（De Quervain tenosynovitis，DQT），但缺乏流行病学证据。本研究旨在使用韩国国家健康保险（National Health Insurance，NHI）数据库估计全国范围内与妊娠相关的 DQT（Pregnancy-related DQT，PRDQT）的发病率，并分析其危险因素。
使用 NHI 理赔数据库对 2013 年至 2017 年期间韩国的孕妇进行了回顾性流行病学研究。使用相应的诊断代码，我们确定了在妊娠或产后期间被诊断为 DQT 的女性。我们计算了累积发病率，并使用多变量逻辑回归分析分析了人口统计学、妊娠类型、分娩方式、妊娠并发症和合并症等危险因素。
在 2013 年至 2017 年期间，在 1601501 名孕妇中，有 34342 名患者被诊断为 PRDQT，累积发病率约为 2.1%。年龄≥30 岁、多胎妊娠、剖宫产、妊娠高血压疾病和潜在的类风湿关节炎均为 PRDQT 发生的显著危险因素，而妊娠糖尿病和潜在的糖尿病则不是。
在韩国，2013 年至 2017 年期间，约每 100 名孕妇中就有 2.1 名患有 PRDQT。本研究中确定的发病率和危险因素可用于临床咨询和预测，以及制定国家卫生政策。
