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[胃癌高低发区胃黏膜病变的比较——3146例手术切除胃标本及112例尸检样本分析。全国胃癌病理协作组]

[Comparison of gastric mucosal lesions in high and low incidence areas of gastric cancer--analysis of 3146 operated gastric specimens and 112 autopsied samples. National Gastric Cancer Pathology Cooperative Group].

出版信息

Zhonghua Zhong Liu Za Zhi. 1987 Jul;9(4):282-5.

PMID:3678018
Abstract

Gastric mucosal lesions, including 3146 gastric specimens resected for various benign diseases and 112 autopsied samples, in both high and low incidence areas of gastric cancer in China were analysed and compared. The results showed that, in high and low incidence areas of gastric cancer, the detection rate was 59.96% and 52.02% for chronic atrophic gastritis, 60.60% and 52.76% for intestinal metaplasia, 37.60% and 22.97% for atypical hyperplasia, 0.44% and 0.13% for microcarcinoma and small carcinoma of the stomach, 2.52% and 0.79% for gastric polyp. The data suggest that a positive correlation be present between the gastric mucosal lesions and gastric cancer. Prevalence of the gastric mucosal lesions in an area may be regarded as an indication of incidence of the gastric cancer. Microcarcinoma and small carcinoma of the stomach were 0.44% of the gastric specimens resected for benign diseases in high incidence area of gastric cancer, which indicates that more tissue sections will have to be taken for examination in order to avoid missing the early carcinoma.

摘要

对中国胃癌高低发区的3146例因各种良性疾病切除的胃标本以及112例尸检样本进行分析和比较,观察胃黏膜病变情况。结果显示,在胃癌高低发区,慢性萎缩性胃炎的检出率分别为59.96%和52.02%;肠化生的检出率分别为60.60%和52.76%;异型增生的检出率分别为37.60%和22.97%;微小胃癌和小胃癌的检出率分别为0.44%和0.13%;胃息肉的检出率分别为2.52%和0.79%。这些数据表明胃黏膜病变与胃癌之间存在正相关。某地区胃黏膜病变的患病率可被视为该地区胃癌发病率的一个指标。在胃癌高发区,微小胃癌和小胃癌占因良性疾病切除胃标本的0.44%,这表明为避免漏诊早期癌,必须多取材检查。

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