Parmeggiani L, Ferrant A, Rodhain J, Michaux J L, Sokal G
Department of Haematology, University of Louvain, Brussels, Belgium.
Eur J Haematol. 1987 Sep;39(3):228-32. doi: 10.1111/j.1600-0609.1987.tb00762.x.
2 patients with myelofibrosis and myeloid metaplasia had symptomatic splenomegaly and were treated with interferon alpha-2c (IFN alpha-2c). The splenic pain and pressure symptoms disappeared, accompanied by a decrease in the size of the spleen. However, the peripheral blood count worsened and no improvement in the bone marrow fibrosis could be observed.
2例骨髓纤维化伴髓外化生患者有症状性脾肿大，接受了α-2c干扰素（IFNα-2c）治疗。脾区疼痛和压迫症状消失，同时脾脏体积减小。然而，外周血细胞计数恶化，且未观察到骨髓纤维化有所改善。
