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早产儿(<35 周胎龄)生后 24 小时内高钠摄入(5mEq/kg/天)的效果:一项非盲随机临床试验。

Effect of High Sodium Intake (5 mEq/kg/day) in Preterm Newborns (<35 Weeks Gestation) During the Initial 24 Hours of Life: A Non-Blinded Randomized Clinical Trial.

机构信息

Hospital del Niño "Dr. Federico Gómez Santos;" Saltillo, Coahuila, México.

出版信息

Indian Pediatr. 2023 Feb 15;60(1):146-148.

PMID:36786184
Abstract

The objective was to analyze effect of early sodium administration in preterm newborns <35 weeks of gestation. The development of hypo- and hyper-natremia, complications, and mortality showed no difference between high sodium and low sodium groups. The percentage of weight loss from birth to 48 hours (7.13% vs 4.08%) and 72 hours (9.02% vs 6.34%) was significantly lower in the high sodium intake group (P=0.036). Early sodium implementation in preterm newborns may improve weight loss and decrease related complications.

摘要

目的在于分析对胎龄<35 周的早产儿进行早期钠补充的效果。高钠组和低钠组在低钠血症和高钠血症的发展、并发症和死亡率方面均无差异。高钠摄入组出生至 48 小时(7.13% 比 4.08%)和 72 小时(9.02% 比 6.34%)体重减轻百分比显著降低(P=0.036)。在早产儿中进行早期钠补充可能有助于减轻体重减轻并减少相关并发症。

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引用本文的文献

1
Effect of early sodium supplementation on weight gain of very preterm infants: a randomised controlled trial.早期补充钠对极早产儿体重增加的影响:一项随机对照试验。
BMJ Paediatr Open. 2025 Jul 13;9(1):e003444. doi: 10.1136/bmjpo-2025-003444.
2
Higher versus lower sodium intake for preterm infants.早产儿高钠与低钠摄入的比较。
Cochrane Database Syst Rev. 2023 Oct 12;10(10):CD012642. doi: 10.1002/14651858.CD012642.pub2.