Department of Gastroenterology, University of Hanyang College of Medicine, Seoul, Republic of Korea.
Department of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea.
Sci Rep. 2023 Feb 14;13(1):2604. doi: 10.1038/s41598-023-29604-x.
The clinical usefulness of repeat colonoscopic polypectomy in patients with numerous polyps has not been sufficiently determined. We aimed to analyze the clinical outcomes of colonoscopic polypectomy with surveillance colonoscopies in patients with ≥ 10 polyps. We reviewed the medical records of 152 patients who underwent polypectomy of ≥ 10 polyps at the baseline colonoscopy. We investigated polyp number, polyp size, polypectomy method, procedure time, and adverse events of the baseline colonoscopy. We also investigated the frequency and interval of surveillance colonoscopies and their findings. The mean number of polyps detected at the baseline colonoscopy was 20.0, of which 16.0 polyps were endoscopically resected. The mean size of the largest polyp was 13.4 mm. The mean procedure time was 54.9 min. Post-polypectomy bleeding occurred in 6 (3.9%) patients, all of whom were treated conservatively. No patients developed perforation. With an increasing number of surveillance colonoscopies, the number of detected polyps and the procedure time decreased. Surveillance colonoscopies identified colorectal cancer only in three patients (2.0%), all of which were mucosal cancers that could be curatively treated by polypectomy. Colonoscopic polypectomy with repeat surveillance colonoscopies is a clinically effective, efficient, and safe management option in patients with ≥ 10 polyps.
在有大量息肉的患者中，重复结肠镜息肉切除术的临床实用性尚未得到充分确定。我们旨在分析结肠镜息肉切除术联合监测结肠镜检查在有≥10 个息肉的患者中的临床结果。我们回顾了在基线结肠镜检查时接受≥10 个息肉息肉切除术的 152 名患者的病历。我们调查了基线结肠镜检查中的息肉数量、息肉大小、息肉切除术方法、手术时间和不良事件。我们还调查了监测结肠镜检查的频率和间隔及其结果。基线结肠镜检查中检测到的平均息肉数量为 20.0 个，其中 16.0 个息肉经内镜切除。最大息肉的平均大小为 13.4mm。平均手术时间为 54.9 分钟。6 名（3.9%）患者发生息肉切除术后出血，均经保守治疗。无患者发生穿孔。随着监测结肠镜检查次数的增加，检出的息肉数量和手术时间减少。监测结肠镜检查仅在 3 名患者（2.0%）中发现结直肠癌，均为可通过息肉切除术治愈的黏膜癌。对于有≥10 个息肉的患者，结肠镜息肉切除术联合重复监测结肠镜检查是一种具有临床有效性、效率和安全性的管理选择。
