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嗜酸性细胞瘤:一种具有恶性特征的罕见良性肾上腺病变。

Oncocytic Tumors: An Uncommon Benign Adrenal Gland Lesions With Features of Malignancy.

作者信息

Elazime Zineb, Elazizi Lamiaa, Aynaou Hayat, Salhi Houda, Elouahabi Hanan

机构信息

Department of Endocrinology, Diabetology, Metabolic Diseases and Nutrition, Hassan II University Hospital Center, Fez, MAR.

出版信息

Cureus. 2023 Jan 11;15(1):e33638. doi: 10.7759/cureus.33638. eCollection 2023 Jan.

Abstract

Oncocytic cell neoplasms are usually found in the thyroid or salivary glands and the kidneys. Adrenal oncocytoma (AO) is an extremely rare localization. It is often non-functional and the suspicion of malignancy is considered when the size of an adrenal incidentaloma is greater than 4 cm. These adrenal oncocytomas, however, are large, round, and encapsulated with a benign presentation and evolution. We report on a 40-year-old male patient. Upon suspicion of a SARS-CoV-2 infection, the general physician instructed a chest CT scan, which, fortuitously, revealed a suspicious left adrenal lesion measuring 62x45mm. A biochemical investigation was negative for either pheochromocytoma or Cushing's syndrome, allowing the recommended surgery to be performed. The anatomopathological analysis showed an uncommon benign adrenal lesion, an adrenal oncocytoma.

摘要

嗜酸性细胞瘤通常见于甲状腺、唾液腺和肾脏。肾上腺嗜酸性细胞瘤(AO)的定位极为罕见。它通常无功能,当肾上腺意外瘤大小大于4cm时,需考虑恶性的可能性。然而,这些肾上腺嗜酸性细胞瘤体积大、呈圆形且有包膜,表现为良性且病程发展平稳。我们报告一例40岁男性患者。因怀疑感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2),全科医生安排了胸部CT扫描,偶然发现左肾上腺有一个可疑病变,大小为62×45mm。生化检查排除了嗜铬细胞瘤或库欣综合征,遂进行了建议的手术。解剖病理学分析显示为一种罕见的肾上腺良性病变——肾上腺嗜酸性细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df9f/9912694/df9b0d57843a/cureus-0015-00000033638-i01.jpg

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