Chen Si E, Iqbal Qamar, Mallappa Sreelakshmi
General Surgery, The Hillingdon Hospitals NHS Foundation Trust, Uxbridge, GBR.
General and Colorectal Surgery, The Hillingdon Hospitals NHS Foundation Trust, Uxbridge, GBR.
Cureus. 2023 Jan 11;15(1):e33666. doi: 10.7759/cureus.33666. eCollection 2023 Jan.
Introduction Accurate diagnosis and prompt definitive management of choledocholithiasis are vital in acute gallstone pancreatitis. The sensitivity of detection of choledocholithiasis varies across imaging modalities. Magnetic resonance cholangiopancreatography (MRCP) is the most sensitive but may not be necessary, resulting in both delayed definitive management and increased costs. We aimed to evaluate the range of radiological investigations patients with acute gallstone pancreatitis underwent and the clinical appropriateness of MRCP when performed. Methods This was an observational study of patients diagnosed with acute gallstone pancreatitis between January 1, 2019 and November 30, 2021 in a district general hospital in London, UK. A detailed review of patient records, laboratory and radiological results, and endoscopic and/or operative intervention was undertaken. Results One hundred consecutive patients diagnosed with acute gallstone pancreatitis (median age 57 years) were included. Seventy-nine had a transabdominal ultrasound (USS), 46 had CT, and 40 patients had MRCP. The median waiting time for these investigations was 1, 0, and 4 days, respectively. Choledocholithiasis was identified in 21 patients (4 on USS, 5 on CT, and 12 on MRCP). As definitive management, 37% underwent endoscopic retrograde cholangiopancreatography, and 57% underwent laparoscopic cholecystectomy. A total of 19% of patients were readmitted with pancreatitis prior to definitive management. Conclusions First-line imaging investigations such as USS and CT can detect some cases of choledocholithiasis in patients with acute gallstone pancreatitis, but not all. Despite expenses in terms of cost and length of hospital stay, MRCP remains an essential resource to detect cases of choledocholithiasis not captured by USS or CT. We recommend establishing a guideline to streamline imaging in assessing acute gallstone pancreatitis.
引言 在急性胆石性胰腺炎中,胆总管结石的准确诊断和及时的确定性治疗至关重要。不同成像方式对胆总管结石的检测敏感性各不相同。磁共振胰胆管造影(MRCP)最为敏感,但可能并非必要,这会导致确定性治疗延迟且成本增加。我们旨在评估急性胆石性胰腺炎患者接受的一系列影像学检查范围以及进行MRCP时的临床合理性。
方法 这是一项对2019年1月1日至2021年11月30日期间在英国伦敦一家区综合医院被诊断为急性胆石性胰腺炎的患者进行的观察性研究。对患者记录、实验室和影像学结果以及内镜和/或手术干预进行了详细回顾。
结果 纳入了100例连续诊断为急性胆石性胰腺炎的患者(中位年龄57岁)。79例患者接受了腹部超声(USS)检查,46例接受了CT检查,40例接受了MRCP检查。这些检查的中位等待时间分别为1天、0天和4天。21例患者被确诊为胆总管结石(4例通过USS发现,5例通过CT发现,12例通过MRCP发现)。作为确定性治疗,37%的患者接受了内镜逆行胰胆管造影,57%的患者接受了腹腔镜胆囊切除术。共有19%的患者在确定性治疗前因胰腺炎再次入院。
结论 诸如USS和CT等一线影像学检查可以检测出部分急性胆石性胰腺炎患者的胆总管结石病例,但并非全部。尽管在成本和住院时间方面有所花费,但MRCP仍然是检测未被USS或CT发现的胆总管结石病例的重要手段。我们建议制定一项指南,以简化评估急性胆石性胰腺炎时的影像学检查流程。