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具有强抗菌活性的红移和 pH 响应型咪唑偶氮染料。

Red-shifted and pH-responsive imidazole-based azo dyes with potent antimicrobial activity.

机构信息

Centre of Chemistry, Department of Chemistry, University of Minho, Campus of Gualtar, Braga 4710-057, Portugal.

Centre for Textile Science and Technology (2C2T), University of Minho, Campus of Azurém, Guimarães 4800-058, Portugal.

出版信息

Chem Commun (Camb). 2023 Mar 2;59(19):2791-2794. doi: 10.1039/d3cc00372h.

DOI:10.1039/d3cc00372h
PMID:36789540
Abstract

A novel route is described to obtain 2-aminoimidazole azo dyes with a unique substituent pattern in the heteroaryl unit that provides halochromic properties, exhibiting vibrant colours that change from magenta to deep blue. Potent antimicrobial properties against infectious yeasts were demonstrated. No cytotoxicity was detected for concentrations lower than 16 μg mL.

摘要

描述了一种获得具有独特杂芳基取代模式的 2-氨基咪唑偶氮染料的新途径,该染料具有变色性质,颜色从洋红变为深蓝色。该染料对传染性酵母具有很强的抗菌性能。在低于 16 μg mL 的浓度下未检测到细胞毒性。

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