Department of Periodontology, School of Life Dentistry at Tokyo, The Nippon Dental University, Chiyoda-ku, Japan.
The Nippon Dental University, Chiyoda-ku, Japan.
Oral Dis. 2024 Apr;30(3):1533-1542. doi: 10.1111/odi.14536. Epub 2023 Feb 28.
The purpose of this study was to verify the accuracy and utility of clinical parameters (plaque index, gingival crevicular fluid volume, probing depth, clinical attachment level, bleeding on probing and gingival index) and biochemical parameters (aspartate aminotransferase, protein and haemoglobin) in a longitudinal analysis during the supportive periodontal therapy period.
A total of 279 test sites of 128 patients were investigated clinically and biochemically. After the first examination of clinical and biochemical parameters, periodontal support treatments were administered immediately and performed once every three months up to the second examination.
All of the clinical and biochemical parameters were significantly lower at the second examination than at the first, except for the plaque index and bleeding on probing. Of these parameters, in particular, aspartate aminotransferase and haemoglobin in the gingival crevicular fluid were significantly reduced compared to those of the first examination in both the ≤4 and ≥5 mm probing depth groups, and they clearly suggested that periodontitis tended to recover.
Adding the haemoglobin test to the bleeding on probing test strongly improves the accuracy of measurement of clinical parameters after periodontal treatment.
本研究旨在验证临床参数（菌斑指数、龈沟液量、探诊深度、临床附着水平、探诊出血和牙龈指数）和生化参数（天门冬氨酸氨基转移酶、蛋白质和血红蛋白）在牙周支持治疗期间的纵向分析中的准确性和实用性。
共对 128 名患者的 279 个试验部位进行了临床和生化检查。在首次检查临床和生化参数后，立即进行牙周支持治疗，并每三个月进行一次，直到第二次检查。
除菌斑指数和探诊出血外，所有临床和生化参数在第二次检查时均显著低于第一次检查。在这些参数中，尤其是在龈沟液中，天门冬氨酸氨基转移酶和血红蛋白在≤4 和≥5mm 探诊深度组中的检测值与第一次检查相比均明显降低，这表明牙周炎有恢复的趋势。
在牙周治疗后，将血红蛋白检测添加到探诊出血检测中，可以显著提高临床参数测量的准确性。
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