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一项在EQUIPPED药物安全项目中采用两种实施策略进行审核与反馈的整群随机试验。

A cluster-randomized trial of two implementation strategies to deliver audit and feedback in the EQUIPPED medication safety program.

作者信息

Vaughan Camille P, Burningham Zach, Kelleher Jessica L, McGwin Gerald, Jasien Christine L, Hastings S Nicole, Stevens Melissa B, Morris Isis, Jackson George L

机构信息

Department of Veterans Affairs, Birmingham/Atlanta Geriatric Research, Education, and Clinical Center, Decatur, Georgia, USA.

Department of Medicine, Division of Geriatrics and Gerontology, Emory University, Atlanta, Georgia, USA.

出版信息

Acad Emerg Med. 2023 Apr;30(4):340-348. doi: 10.1111/acem.14697. Epub 2023 Mar 8.

Abstract

OBJECTIVES

The Enhancing the Quality of Prescribing Practices for Older Adults Discharged from the Emergency Department (EQUIPPED) medication safety program involves three core components including provider education, clinical decision support, and audit and feedback using the American Geriatrics Society Beers Criteria to determine potentially inappropriate medications (PIMs). This study evaluated implementation of audit and feedback through a centralized informatics-based dashboard compared to academic detailing delivered one on one by an EQUIPPED champion.

METHODS

In a cluster-randomized study (October 2019-September 2021), eight VA emergency department (EDs) implemented either the academic detailing (n = 4) or the dashboard (n = 4) strategy for the audit and feedback component of EQUIPPED. The primary outcome was the monthly proportion of PIMs prescribed to Veterans 65 years or older at ED discharge. Poisson regression was used to evaluate the proportion of PIMs prescribed 6 months prior to EQUIPPED implementation compared to 12 months following implementation.

RESULTS

Eight VA ED sites successfully implemented the EQUIPPED program. During the 6-month baseline period, the academic detailing and dashboard sites had similar PIM prescribing rates of 8.01% for academic detailing versus 8.04% for dashboard (p = 0.90). Comparing 12 months of prescribing data after EQUIPPED implementation, the academic detailing group significantly improved PIM prescribing (7.07%) compared to the dashboard group (8.10%; odds ratio 1.14, 95% confidence interval 1.08-1.22, p ≤ 0.0001). Within the groups, two of the four academic detailing sites demonstrated statistically significant reductions in PIM prescribing. One of the four dashboard sites achieved nearly 50% relative reduction in PIM prescribing.

CONCLUSIONS

Eight VA EDs successfully implemented the core components of the EQUIPPED program amid the unprecedented challenges posed by the COVID-19 pandemic. While the academic detailing approach to EQUIPPED audit and feedback was more effective at the group level to improve safe prescribing for older Veterans discharged from the ED, the trial suggests that dashboard-based audit and feedback is a reasonable strategy in resource-limited settings.

摘要

目的

提高急诊科出院的老年人处方质量(EQUIPPED)药物安全项目包含三个核心组成部分,即提供者教育、临床决策支持以及使用美国老年医学会Beers标准进行审核与反馈,以确定潜在不适当用药(PIM)。本研究评估了通过基于信息学的集中式仪表盘进行审核与反馈的实施情况,并与由EQUIPPED倡导者一对一提供的学术详情介绍进行了比较。

方法

在一项整群随机研究(2019年10月至2021年9月)中,八个退伍军人事务部(VA)急诊科对EQUIPPED审核与反馈部分实施了学术详情介绍策略(n = 4)或仪表盘策略(n = 4)。主要结局是在急诊科出院时给65岁及以上退伍军人开具的PIM的月度比例。使用泊松回归来评估EQUIPPED实施前6个月与实施后12个月开具的PIM比例。

结果

八个VA急诊科成功实施了EQUIPPED项目。在6个月的基线期内,学术详情介绍组和仪表盘组的PIM处方率相似,学术详情介绍组为8.01%,仪表盘组为8.04%(p = 0.90)。比较EQUIPPED实施后的12个月处方数据,学术详情介绍组的PIM处方情况(7.07%)相比仪表盘组(8.10%)有显著改善(优势比1.14,95%置信区间1.08 - 1.22,p≤0.0001)。在各小组中,四个学术详情介绍站点中的两个在PIM处方方面显示出统计学上的显著减少。四个仪表盘站点中的一个在PIM处方方面实现了近50%的相对减少。

结论

在COVID - 19大流行带来的前所未有的挑战中,八个VA急诊科成功实施了EQUIPPED项目的核心组成部分。虽然EQUIPPED审核与反馈的学术详情介绍方法在群体层面上对于改善从急诊科出院的老年退伍军人的安全处方更有效,但该试验表明,在资源有限的环境中,基于仪表盘的审核与反馈是一种合理的策略。

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